Pharmacology and Toxicology

Vascular injury associated with ethanol intake is driven by AT1 receptor and mitochondrial dysfunction
Wanessa M.C. Awata, Juliano V. Alves, Rafael M. Costa, Ariane Bruder-Nascimento, Shubhnita Singh, Gabriela S. Barbosa, Carlos Renato Tirapelli, Thiago Bruder-Nascimento

bioRxiv 2023.09.05.556341; doi: https://doi.org/10.1101/2023.09.05.556341 New Results

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Thymoquinone-Protoflavone Hybrid Molecules as Potential Antitumor Agents
Sara H. H. Ahmed, Bizhar A. Tayeb, Tímea Gonda, Gábor Girst, Kornél Szőri, Róbert Berkecz, István Zupkó, Renáta Minorics, Attila Hunyadi

bioRxiv 2023.09.04.555971; doi: https://doi.org/10.1101/2023.09.04.555971 New Results

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Assessing Per- and Polyfluoroalkyl Substances (PFAS) in Fish Fillet Using Non-Targeted Analyses
Anna K. Boatman, Jessie R. Chappel, Madison E. Polera, James N. Dodds, Scott M. Belcher, Erin S. Baker

bioRxiv 2023.09.01.555938; doi: https://doi.org/10.1101/2023.09.01.555938 New Results

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PROTAC-mediated Degradation of HIV-1 Nef Efficiently Restores Cell-surface CD4 and MHC-I Expression and Blocks HIV-1 Replication
Lori A. Emert-Sedlak, Colin M. Tice, Haibin Shi, John J. Alvarado, Sherry T. Shu, Allen B. Reitz, Thomas E. Smithgall

bioRxiv 2023.08.14.553289; doi: https://doi.org/10.1101/2023.08.14.553289 New Results

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GLP-1 Receptor Agonist Improves Metabolic Disease in a Pre-clinical Model of Lipodystrophy
Ahlima Roumane, George D. Mcilroy, Nadine Sommer, Weiping Han, Lora K. Heisler, Justin J. Rochford

bioRxiv 2023.09.01.555852; doi: https://doi.org/10.1101/2023.09.01.555852 New Results

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Exploration of the main active metabolites from Tinospora crispa (L.) Hook. f. & Thomson stem as insulin sensitizer in L6.C11 skeletal muscle cell by integrating in vitro, metabolomics, and molecular docking
Ummu Mastna Zuhri, Nancy Dewi Yuliana, Fadilah Fadilah, Linda Erlina, Erni Hernawati Purwaningsih, Alfi Khatib

bioRxiv 2023.09.01.555830; doi: https://doi.org/10.1101/2023.09.01.555830 New Results

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Meisoindigo: An Effective Inhibitor of SARS-CoV-2 Main Protease Revealed by Yeast System
Wojciech Grabiński, Anna Kicińska, Ewa Kosicka, Martyna Baranek-Grabińska, Ewelina D Hejenkowska, Joanna Budzik, Paulina Śliska, Weronika Śliwińska, Andonis Karachitos

bioRxiv 2023.09.03.555867; doi: https://doi.org/10.1101/2023.09.03.555867 New Results

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Effects of nitrous oxide and ketamine on the prefrontal cortex in mice: a comparative study
Stanislav Rozov, Roosa Saarreharju, Stanislav Khirug, Markus Storvik, Claudio Rivera, Tomi Rantamäki

bioRxiv 2022.09.19.508563; doi: https://doi.org/10.1101/2022.09.19.508563 New Results

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Is the neuropeptide PEN a ligand of GPR83?
Yvonne Giesecke, Vahid Asimi, Valentina Stulberg, Gunnar Kleinau, Patrick Scheerer, Beate Koksch, Carsten Grötzinger

bioRxiv 2023.08.31.555736; doi: https://doi.org/10.1101/2023.08.31.555736 Contradictory Results

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A benzoxazolylurea inhibits VraS and enhances antimicrobials against vancomycin intermediate-resistant Staphylococcus aureus
Emerson P. Heckler, Liaqat Ali, Shrijan Bhattarai, Brittnee Cagle-White, Nicklaus Smith, Robert A. Coover, May H. Abdel Aziz, Aurijit Sarkar

bioRxiv 2023.08.31.555806; doi: https://doi.org/10.1101/2023.08.31.555806 New Results

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Pharmacology and Toxicology

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