Pharmacology and Toxicology

In vivo Antidiarrheal activities of the hydro alcoholic extracts of Schinus molle L. (Anarcardiaceae) leaf in mice
Getnet Mengistu, Kidan Hailay, Desye Misganaw, Abel Andualem, Yaschilal Muche Belayneh

bioRxiv 2022.07.06.499014; doi: https://doi.org/10.1101/2022.07.06.499014 New Results

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Immature human engineered heart tissues engraft in a guinea pig chronic injury model
Constantin von Bibra, Aya Shibamiya, Andrea Bähr, Birgit Geertz, Maria Köhne, Tim Stuedemann, Jutta Starbatty, Nadja Hornaschewitz, Xinghai Li, Eckhard Wolf, Nikolai Klymiuk, Markus Krane, Christian Kupatt, Bernhard Hiebl, Thomas Eschenhagen, Florian Weinberger

bioRxiv 2022.07.07.499077; doi: https://doi.org/10.1101/2022.07.07.499077 New Results

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Flavor Classification/Categorization and Differential Toxicity of Oral Nicotine Pouches (ONPs) in Lung Epithelial Cells
Sadiya Shaikh, Wai Cheung Tung, Joseph Lucas, Shaiesh Yogeswaran, Dongmei Li, Irfan Rahman

bioRxiv 2022.07.06.498919; doi: https://doi.org/10.1101/2022.07.06.498919 New Results

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Cisplatin toxicity is mediated by direct binding to TLR4 through a mechanism that is distinct from metal allergens
Ivan K. Domingo, Jody Groenendyk, Marek Michalak, Amit P. Bhavsar

bioRxiv 2022.07.06.498982; doi: https://doi.org/10.1101/2022.07.06.498982 New Results

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Sublethal and transgenerational effects of lambda-cyhalothrin and abamectin on the development and reproduction of Cydia pomonella
Di Ju, Yu-Xi Liu, Xue Liu, Youssef Dewer, David Mota-Sanchez, Xue-Qing Yang

bioRxiv 2022.07.05.498911; doi: https://doi.org/10.1101/2022.07.05.498911 New Results

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First-in-patient dose prediction for adeno-associated virus-mediated hemophilia gene therapy using allometric scaling
Peng Zou

bioRxiv 2022.07.05.498837; doi: https://doi.org/10.1101/2022.07.05.498837 New Results

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Receptor levels determine binding affinity of WNT-3A to Frizzled 7 in a colorectal cancer model
Lukas Grätz, Joanna J. Sajkowska-Kozielewicz, Janine Wesslowski, Katja Petzold, Gary Davidson, Gunnar Schulte, Paweł Kozielewicz

bioRxiv 2022.07.04.498383; doi: https://doi.org/10.1101/2022.07.04.498383 New Results

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Fetal imidacloprid causes ASD-like impairment of biological motion perception in neonatal chicks
Toshiya Matsushima, Momoko Miura, Nina Patzke, Noriyuki Toji, Kazuhiro Wada, Yukiko Ogura, Koichi J. Homma, Paola Sgadò, Giorgio Vallortigara

bioRxiv 2022.05.19.492744; doi: https://doi.org/10.1101/2022.05.19.492744 New Results

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Complement receptor C5aR1 signaling in sensory neuron-associated macrophages drives neuropathic pain
Andreza U. Quadros, Alexandre G. M. Maganin, Conceição E. A. Silva, Samara Damasceno, Maria C. M. Cavallini, Marcela Davoli-Ferreira, Alexandre H. P. Lopes, Devi R. Sagar, Laura Brandolini, Sang Hoon Lee, Jose C. Alves-Filho, Fernando Q. Cunha, Temugin Berta, Jörg Köhl, Marcello Allegretti, Victoria Chapman, Thiago M. Cunha

bioRxiv 2022.07.01.498487; doi: https://doi.org/10.1101/2022.07.01.498487 New Results

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Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
Lijuan Xu, Xinyao Zhang, Yin Zhao, Yang Cao, Yuanbo Liang

bioRxiv 2022.06.30.498232; doi: https://doi.org/10.1101/2022.06.30.498232 New Results

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Pharmacology and Toxicology

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