Pharmacology and Toxicology

COMPARATIVE PHYTOCHEMICAL ANALYSIS OF TWO ALPINIA SPECIES FROM ZINGEBERACEAE FAMILY
N. Rabita, K. Palanisamy

bioRxiv 2023.10.25.564021; doi: https://doi.org/10.1101/2023.10.25.564021 New Results

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Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity
Brian J. Bender, Julie E. Pickett, Joao Braz, Hye Jin Kang, Stefan Gahbauer, Karnika Bhardwaj, Sian Rodriguez-Rosado, Yongfeng Liu, Manish Jain, Allan I. Basbaum, Bryan L. Roth, Brian K. Shoichet

bioRxiv 2023.10.25.564029; doi: https://doi.org/10.1101/2023.10.25.564029 New Results

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High-content fluorescence bioassay to investigate pore formation, ion channel modulation and cell membrane lysis induced by venoms
Simon Kramer, Charan Kotapati, Yuanzhao Cao, Bryan G Fry, Nathan J Palpant, Glenn F King, Fernanda C Cardoso

bioRxiv 2023.10.25.563942; doi: https://doi.org/10.1101/2023.10.25.563942 New Results

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Alpha-Asarone Attenuates Alcohol-Induced Hepatotoxicity in a Murine Model by Ameliorating Oxidative Stress, Inflammation, and Modulating Apoptotic-Autophagic Cell Death
Amir Mohamed Abdelhamid, Nada A.M. Ali, Norhan M. El Sayed, Asmaa Radwan

bioRxiv 2023.10.24.563724; doi: https://doi.org/10.1101/2023.10.24.563724 New Results

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Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Bartlomiej Porebski, Wanda Christ, Alba Corman, Martin Haraldsson, Myriam Barz, Louise Lidemalm, Maria Häggblad, Juliana Ilmain, Shane C. Wright, Matilde Murga, Jan Shlegel, Erdinc Sezgin, Gira Bhabha, Volker M Lauschke, Miguel Lafarga, Jonas Klingström, Daniela Huhn, Oscar Fernandez-Capetillo

bioRxiv 2023.10.25.563967; doi: https://doi.org/10.1101/2023.10.25.563967 New Results

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Targeting cancer with small molecule pan-KRAS degraders
Johannes Popow, William Farnaby, Andreas Gollner, Christiane Kofink, Gerhard Fischer, Melanie Wurm, David Zollman, Andre Wijaya, Nikolai Mischerikow, Carina Hasenoehrl, Polina Prokofeva, Heribert Arnhof, Silvia Arce-Solano, Sammy Bell, Georg Boeck, Emelyne Diers, Aileen B. Frost, Jake Goodwin-Tindall, Jale Karolyi-Oezguer, Shakil Khan, Theresa Klawatsch, Manfred Koegl, Roland Kousek, Barbara Kratochvil, Katrin Kropatsch, Arnel A. Lauber, Ross McLennan, Sabine Olt, Daniel Peter, Oliver Petermann, Vanessa Roessler, Peggy Stolt-Bergner, Patrick Strack, Eva Strauss, Nicole Trainor, Vesna Vetma, Claire Whitworth, Siying Zhong, Jens Quant, Harald Weinstabl, Bernhard Kuster, Peter Ettmayer, Alessio Ciulli

bioRxiv 2023.10.24.563163; doi: https://doi.org/10.1101/2023.10.24.563163 New Results

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WITHDRAWN: L-Carnitine on contrast-induced nephropathy in diabetic rats
Natalia Abreu de Oliveira, Sheila Marques Fernandes Couto, Fernanda Teixeira Borges, Maria de Fátima Fernandes Vattimo, Cassiane Dezoti da Fonseca

bioRxiv 2023.08.10.552846; doi: https://doi.org/10.1101/2023.08.10.552846 Withdrawn

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Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity
Richard T. Eastman, Radda Rusinova, Karl F. Herold, Xi-Ping Huang, Patricia Dranchak, Ty C. Voss, Sandeep Rana, Jonathan H. Shrimp, Alex D. White, Hugh C. Hemmings Jr., Bryan L. Roth, James Inglese, Olaf S. Andersen, Jayme L. Dahlin

bioRxiv 2023.10.23.563088; doi: https://doi.org/10.1101/2023.10.23.563088 New Results

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Feasibility of intranasal delivery of thin-film freeze-dried monoclonal antibodies
Yu-Sheng Yu, Haiyue Xu, Khaled AboulFotouh, Gerallt Williams, Julie Suman, Sawittree Sahakijpijarn, Chris Cano, Zachary N. Warnken, Kevin C.-W. Wu, Robert O. Williams III, Zhengrong Cui

bioRxiv 2023.10.23.563139; doi: https://doi.org/10.1101/2023.10.23.563139 New Results

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Support Vector Machine based prediction models for drug repurposing and designing novel drugs for colorectal cancer
Avik Sengupta, Rahul Kumar

bioRxiv 2023.10.20.563215; doi: https://doi.org/10.1101/2023.10.20.563215 New Results

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Pharmacology and Toxicology

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