Pharmacology and Toxicology

Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126
Robin Mesnage, Martina Biserni, Sucharitha Balu, Clement Frainay, Nathalie Poupin, Fabien Jourdan, Eva Wozniak, Theodoros Xenakis, Charles A Mein, Michael A Antoniou

bioRxiv 259093; doi: https://doi.org/10.1101/259093 New Results
Addressing the Most Neglected Diseases through an Open Research Model: the Discovery of Fenarimols as Novel Drug Candidates for Eumycetoma
Wilson Lim, Youri Melse, Mickey Konings, Hung Phat Duong, Kimberly Eadie, Benoit Laleu, Ben Perry, Matthew Todd, Jean-Robert Ioset, Wendy van de Sande

bioRxiv 258905; doi: https://doi.org/10.1101/258905 New Results
Inhibition of CaOx crystals by Neolamarckia cadamba: An in vivo approach
Prathibha Nair

bioRxiv 253179; doi: https://doi.org/10.1101/253179 Confirmatory Results
Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain
Brice Bellessort, Anne Bachelot, Virginie Grouthier, Camille De Lombares, Nicolas Narboux-Nême, Paolo Garagnani, Chiara Pirazzini, Simonetta Astigiano, Luca Mastracci, Anastasia Fontaine, Gladys Alfama, Evelyne Duvernois-Berthet, Giovanni Levi

bioRxiv 251397; doi: https://doi.org/10.1101/251397 New Results
Improving the Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models
Theodore R. Rieger, Richard J. Allen, Lukas Bystricky, Yuzhou Chen, Glen Colopy, Yifan Cui, Angelica Gonzalez, Yifei Liu, Rebekah White, Rebecca Everett, H. T. Banks, Cynthia J. Musante

bioRxiv 196089; doi: https://doi.org/10.1101/196089 New Results
Navigating in vitro bioactivity data: investigating available resources using model compounds
Sten Ilmjarv, Fiona Augsburger, Jerven Tjalling Bolleman, Robin Liechti, Alan Bridge, Jenny Sandstrom, Vincent Jaquet, Ioannis Xenarios, Karl-Heinz Krause

bioRxiv 248898; doi: https://doi.org/10.1101/248898 New Results
Precautionary Coherence Unravels Dose Escalation Designs
David C. Norris

bioRxiv 240846; doi: https://doi.org/10.1101/240846 New Results
Broad spectrum proteomics analysis of the inferior Colliculus following acute hydrogen sulfide exposure
Dong-Suk Kim, Poojya Anantharam, Andrea Hoffman, Mitchell L Meade, Nadja Grobe, Jeffery M Gearhart, Elizabeth M Whitley, Belinda Mahama, Wilson K Rumbeiha

bioRxiv 237370; doi: https://doi.org/10.1101/237370 New Results
Silver microwires from treating tooth decay with silver diamine fluoride
Jong Seto, Jeremy A. Horst, Dilworth Y. Parkinson, John C. Frachella, Joseph L. DeRisi

bioRxiv 152199; doi: https://doi.org/10.1101/152199 New Results
Non-blocking modulation as the major mechanism of sodium channel inhibition by riluzole
Anett K Szabo, Krisztina Pesti, Peter Lukacs, Matyas C Foldi, Zoltan Gerevich, Beata Sperlagh, Arpad Mike

bioRxiv 228569; doi: https://doi.org/10.1101/228569 New Results

Pharmacology and Toxicology

Pages