Pharmacology and Toxicology

Pharmacological Characterisation of Novel Adenosine Receptor A₃R Antagonists
Kerry Barkan, Panagiotis Lagarias, Margarita Stampelou, Dimitrios Stamatis, Sam Hoare, Karl-Norbert Klotz, Eleni Vrontaki, Antonios Kolocouris, Graham Ladds

bioRxiv 693796; doi: https://doi.org/10.1101/693796 New Results

Add to Selected Citations
Repurposing Pyramax® for the Treatment of Ebola Virus Disease: Additivity of the Lysosomotropic Pyronaridine and Non-Lysosomotropic Artesunate
Thomas R. Lane, Julie Dyall, Luke Mercer, Caleb Goodin, Daniel H. Foil, Huanying Zhou, Elena Postnikova, Janie Y. Liang, Michael R. Holbrook, Peter B. Madrid, Sean Ekins

bioRxiv 2020.04.25.061333; doi: https://doi.org/10.1101/2020.04.25.061333 New Results

Add to Selected Citations
Cytotoxicity evaluation of chloroquine and hydroxychloroquine in multiple cell lines and tissues by dynamic imaging system and PBPK model
Jianling Yang, Meng Wu, Xu Liu, Qi Liu, Zhengyang Guo, Xueting Yao, Yang Liu, Cheng Cui, Haiyan Li, Chunli Song, Dongyang Liu, Lixiang Xue

bioRxiv 2020.04.22.056762; doi: https://doi.org/10.1101/2020.04.22.056762 New Results

Add to Selected Citations
A Library of Nucleotide Analogues Terminate RNA Synthesis Catalyzed by Polymerases of Coronaviruses Causing SARS and COVID-19
Steffen Jockusch, Chuanjuan Tao, Xiaoxu Li, Thomas K. Anderson, Minchen Chien, Shiv Kumar, James J. Russo, Robert N. Kirchdoerfer, Jingyue Ju

bioRxiv 2020.04.23.058776; doi: https://doi.org/10.1101/2020.04.23.058776 New Results

Add to Selected Citations
Inhibitory effect of eslicarbazepine acetate and S-licarbazepine on Na_v1.5 channels
Theresa K. Leslie, Lotte Brückner, Sangeeta Chawla, William J. Brackenbury

bioRxiv 2020.04.24.059188; doi: https://doi.org/10.1101/2020.04.24.059188 New Results

Add to Selected Citations
The anti-lipidemic drug simvastatin modulates Epigenetic Biomarkers in the Amphipod Gammarus locusta
Nélson Alves, Teresa Neuparth, Susana Barros, Miguel M. Santos

bioRxiv 2020.04.23.058248; doi: https://doi.org/10.1101/2020.04.23.058248 New Results

Add to Selected Citations
Selectivity Landscape of 100 Therapeutically Relevant GPCR Profiled by an Effector Translocation-Based BRET Platform
Charlotte Avet, Arturo Mancini, Billy Breton, Christian Le Gouill, Alexander S. Hauser, Claire Normand, Hiroyuki Kobayashi, Florence Gross, Mireille Hogue, Viktoriya Lukasheva, Sandra Morissette, Eric Fauman, Jean-Philippe Fortin, Stephan Schann, Xavier Leroy, David E. Gloriam, Michel Bouvier

bioRxiv 2020.04.20.052027; doi: https://doi.org/10.1101/2020.04.20.052027 New Results

Add to Selected Citations
Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model
Matthew Dent, Krystal Hamorsky, Thibaut Vausselin, Jean Dubuisson, Yoshinari Miyata, Yoshio Morikawa, Nobuyuki Matoba

bioRxiv 2020.04.22.056754; doi: https://doi.org/10.1101/2020.04.22.056754 New Results

Add to Selected Citations
Δ⁹-Tetrahydrocannabinol (THC) impairs visual working memory performance: A randomized crossover trial
Kirsten C. S. Adam, Manoj K. Doss, Elisa Pabon, Edward K. Vogel, Harriet de Wit

bioRxiv 778068; doi: https://doi.org/10.1101/778068 New Results

Add to Selected Citations
Ligand-directed covalent labelling of a GPCR with a fluorescent tag
Leigh A Stoddart, Nicholas D Kindon, Omolade Otun, Clare R. Harwood, Foteini Patera, Dmitry B Veprintsev, Jeanette Woolard, Stephen J Briddon, Hester A Franks, Stephen J Hill, Barrie Kellam

bioRxiv 2020.04.21.053405; doi: https://doi.org/10.1101/2020.04.21.053405 New Results

Add to Selected Citations

Pharmacology and Toxicology

Pages