Pharmacology and Toxicology

An antibody drug conjugate targeting a GSTA glycosite-signature epitope of mucin1 expressed by non-small cell lung cancer
Deng Pan, Yubo Tang, Jiao Tong, Chengmei Xie, Jiaxi Chen, Chunchao Feng, Patrick Hwu, Wei Huang, Dapeng Zhou

bioRxiv 2019.12.22.885566; doi: https://doi.org/10.1101/2019.12.22.885566 New Results

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Reclassification of SLC22 Transporters: Analysis of OAT, OCT, OCTN, and other Family Members Reveals 8 Functional Subgroups
Darcy Engelhart, Jeffry C. Granados, Da Shi, Milton Saier Jr., Michael Baker, Ruben Abagyan, Sanjay K. Nigam

bioRxiv 2019.12.23.887299; doi: https://doi.org/10.1101/2019.12.23.887299 New Results

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Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms
Andrew K. Smith, Glen E.P. Ropella, Mitchell R. McGill, Preethi Krishnan, Lopamudra Dutta, Ryan C. Kennedy, Hartmut Jaeschke, C. Anthony Hunt

bioRxiv 2019.12.24.887869; doi: https://doi.org/10.1101/2019.12.24.887869 New Results

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Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights
Stanley E. Lazic, Elizaveta Semenova, Dominic P. Williams

bioRxiv 754853; doi: https://doi.org/10.1101/754853 New Results

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An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias
Jennifer L. Wilson, Dan Lu, Nick Corr, Aaron Fullerton, James Lu

bioRxiv 2019.12.23.886960; doi: https://doi.org/10.1101/2019.12.23.886960 New Results

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Parental effects via glyphosate-based herbicides in a bird model?
Suvi Ruuskanen, Miia Rainio, Maiju Uusitalo, Kari Saikkonen, Marjo Helander

bioRxiv 2019.12.21.885855; doi: https://doi.org/10.1101/2019.12.21.885855 New Results

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Adding insult to injury: Effects of chronic oxybenzone exposure and elevated temperature on two reef-building corals
Tim Wijgerde, Mike van Ballegooijen, Reindert Nijland, Luna van der Loos, Christiaan Kwadijk, Ronald Osinga, Albertinka Murk, Diana Slijkerman

bioRxiv 2019.12.19.882332; doi: https://doi.org/10.1101/2019.12.19.882332 New Results

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Webina: An Open-Source Library and Web App that Runs AutoDock Vina Entirely in the Web Browser
Yuri Kochnev, Erich Hellemann, Kevin C. Cassidy, Jacob D. Durrant

bioRxiv 2019.12.18.881789; doi: https://doi.org/10.1101/2019.12.18.881789 New Results

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Microplastic vector effects: are fish at risk when exposed via the trophic chain?
Agathe Bour, Joachim Sturve, Johan Höjesjö, Bethanie Carney Almroth

bioRxiv 2019.12.17.879478; doi: https://doi.org/10.1101/2019.12.17.879478 New Results

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In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3
Gerard Callejo, Luke A. Pattison, Jack C. Greenhalgh, Sampurna Chakrabarti, Evangelia Andreopoulou, James R. F. Hockley, Ewan St. John Smith, Taufiq Rahman

bioRxiv 704445; doi: https://doi.org/10.1101/704445 New Results

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Pharmacology and Toxicology

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