Pharmacology and Toxicology

The Utilization of Pharmacophore-based 3D QSAR Modeling and Virtual Screening in Safety Profiling: a Case Study to Identify Antagonistic Activities against Adenosince Receptor, A2aR, using 1,897 known drugs
Fan Fan, Hisham Hamadeh, Dora Toledo Warshaviak, Robert Dunn

bioRxiv 413385; doi: https://doi.org/10.1101/413385 New Results
Primary Target Prediction of Bioactive Molecules from Chemical Structure
Abed Forouzesh, Sadegh Samadi Foroushani, Fatemeh Forouzesh, Eskandar Zand

bioRxiv 413237; doi: https://doi.org/10.1101/413237 New Results
DNMT inhibitors increase methylation of CpGs related to p53 pathway genes in colon, lymphoma, bladder, ovarian, and breast cancer cells
Anil K Giri, Tero Aittokallio

bioRxiv 395467; doi: https://doi.org/10.1101/395467 New Results
Hydrophobic organic contaminants are not linked to microplastic uptake in Baltic Sea herring
Martin Ogonowski, Viktoria Wenman, Sara Danielsson, Elena Gorokhova

bioRxiv 363127; doi: https://doi.org/10.1101/363127 New Results
TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance
Martin Michaelis, Constanze Schneider, Florian Rothweiler, Tamara Rothenburger, Marco Mernberger, Andrea Nist, Andreas von Deimling, Daniel Speidel, Thorsten Stiewe, Jindrich Cinatl Jr.

bioRxiv 404475; doi: https://doi.org/10.1101/404475 New Results
Incorporation of doxorubicin in different polymer nanoparticles and their anti-cancer activity
S Pieper, Hannah Onafuye, Dennis Mulac, Jindrich Cinatl, Mark N Wass, Martin Michaelis, Klaus Langer

bioRxiv 403923; doi: https://doi.org/10.1101/403923 New Results
A serial dilution method for assessment of microplastic toxicity in suspension
Zandra Gerdes, Markus Hermann, Martin Ogonowski, Elena Gorokhova

bioRxiv 401331; doi: https://doi.org/10.1101/401331 New Results
Positive human health effects of sea spray aerosols: molecular evidence from exposed lung cell lines.
Jana Asselman, Emmanuel Van Acker, Maarten De Rijcke, Laurentijn Tilleman, Filip Van Nieuwerburgh, Jan Mees, Karel De Schamphelaere, Colin Janssen

bioRxiv 397141; doi: https://doi.org/10.1101/397141 New Results
Dimethylarsenic acid (DMA) accumulation positively correlates with realgar-induced subchronic toxicity in rats
YAN YI, Shuangrong Gao, Jing Xia, Yong Zhao, Chunying Li, Yushi Zhang, Lianmei Wang, Chen Pan, Suyan Liu, Jiayin Han, Aihua Liang, Shen Ji

bioRxiv 398206; doi: https://doi.org/10.1101/398206 New Results
Farmers perceptions on the causes of cassava root bitterness in konzo-affected areas of Mtwara Region, Tanzania
Matema Lileko Emily Imakumbili, Ernest Semu, Johnson M.R. Semoka, Adebayo Abass, Geoffrey Mkamilo

bioRxiv 397018; doi: https://doi.org/10.1101/397018 New Results

Pharmacology and Toxicology

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