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Pharmacology and Toxicology

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  • Selection Of Theaflavin 2B As a Potential HSP90 Antagonist Semi-rigid Ligand Docking Analysis
    Samuel Akinsehinwa, Oluwatobi Medayedupin
    bioRxiv 2022.06.24.497557; doi: https://doi.org/10.1101/2022.06.24.497557 New Results
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  • Toxicological study on methanol root bark extract of Acacia sieberiana (Fabaceae) in Wistar rats
    Miriam Watafua, Jane I. Ejiofor, Aminu Musa, Mubarak Hussaini Ahmad
    bioRxiv 2022.06.24.497563; doi: https://doi.org/10.1101/2022.06.24.497563 New Results
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  • Underlying beneficial effects of Rhubarb on constipation-induced inflammation, disorder of gut microbiome and metabolism
    Han Gao, Chengwei He, Rongxuan Hua, Chen Liang, Boya Wang, Yixuan Du, Yuexin Guo, Lei Gao, Lucia Zhang, Hongwei Shang, Jingdong Xu
    bioRxiv 2022.06.24.497289; doi: https://doi.org/10.1101/2022.06.24.497289 New Results
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  • Artemisia extracts Differ from Artemisinin Effects on Human Hepatic CYP450s 2B6 and 3A4 in vitro
    Ndeye F. Kane, Bushra H. Kiani, Matthew R. Desrosiers, Melissa J. Towler, Pamela J. Weathers
    bioRxiv 2022.06.24.497548; doi: https://doi.org/10.1101/2022.06.24.497548 New Results
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  • RyR2 inhibition with dantrolene is antiarrhythmic, antifibrotic, and improves cardiac function in chronic ischemic heart disease
    Jeffrey Schmeckpeper, Kyungsoo Kim, Sharon A George, Dan Blackwell, Jaclyn A Brennan, Igor R Efimov, Bjorn C Knollmann
    bioRxiv 2022.06.24.496861; doi: https://doi.org/10.1101/2022.06.24.496861 New Results
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  • Toxicity of House Cricket (Acheta domesticus) in Mice
    Matano Yasuki, Sakagami Kiyo, Nojiri Yuuto, Nomura Kenta, Masuda Akira, Moriike Yuuki, Yamamoto Akane, Nagai Nobuo, Ogura Atsushi
    bioRxiv 2022.06.23.497304; doi: https://doi.org/10.1101/2022.06.23.497304 New Results
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  • Acacia sieberiana (Fabaceae) Attenuates Paracetamol and Bile Duct Ligation-Induced Hepatotoxicity via Modulation of Biochemical and Oxidative Stress Biomarkers
    Miriam Watafua, Jane I. Ejiofor, Aminu Musa, Mubarak Hussaini Ahmad
    bioRxiv 2022.06.22.497272; doi: https://doi.org/10.1101/2022.06.22.497272 New Results
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  • Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans
    Danielle Ireland, Christina Rabeler, TaiXi Gong, Eva-Maria S. Collins
    bioRxiv 2022.06.20.496885; doi: https://doi.org/10.1101/2022.06.20.496885 New Results
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  • Nose-only Exposure to Cherry and Tobacco Flavored E-cigarettes Induced Lung Inflammation in Mice in a Sex-dependent Manner
    Thomas Lamb, Thivanka Muthumalage, Jiries Meehan-Atrash, Irfan Rahman
    bioRxiv 2022.06.20.496875; doi: https://doi.org/10.1101/2022.06.20.496875 New Results
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  • E-Cigarette Synthetic Cooling Agent WS-23 and Nicotine Aerosols Differentially Modulate Airway Epithelial Cell Responses
    Marko Manevski, Dinesh Devadoss, Shaiesh Yogeswaran, Irfan Rahman, Hitendra S. Chand
    bioRxiv 2022.06.20.496868; doi: https://doi.org/10.1101/2022.06.20.496868 New Results
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