Pharmacology and Toxicology

Quinoa as Functional Food? Urinary elimination of ecdysterone after consumption of quinoa alone and in combination with spinach
Eduard Isenmann, Tasha Yuliandra, Konstantina Touvleliou, Matthias Broekmann, Xavier de la Torre, Francesco Botrè, Patrick Diel, Maria Kristina Parr

bioRxiv 2023.10.10.560427; doi: https://doi.org/10.1101/2023.10.10.560427 New Results

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Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting
Rachel K. Morgan, Kai Wang, Laurie K. Svoboda, Christine A. Rygiel, Claudia Lalancette, Raymond Cavalcante, Marisa S. Bartolomei, Rexxi Prasasya, Kari Neier, Bambarendage P.U. Perera, Tamara R Jones, Justin A. Colacino, Maureen A. Sartor, Dana C. Dolinoy

bioRxiv 2023.09.29.560131; doi: https://doi.org/10.1101/2023.09.29.560131 New Results

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Fluorescent pH-sensing bandage for point-of-care wound diagnostics
Marie-Lynn Al-Hawat, Léo-Paul Tricou, Katia Cherifi, Stéphanie Lamontagne, Minh Tran, Amy Ching Yie Ngu, Gabriela Manrique, Natalie Guirguis, Arturo Israel Machuca-Parra, Simon Matoori

bioRxiv 2023.10.08.561402; doi: https://doi.org/10.1101/2023.10.08.561402 New Results

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Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues
Muhammad Murtaza Hassan, Yen-Der Li, Michelle W. Ma, Mingxing Teng, Woong Sub Byun, Kedar Puvar, Ryan Lumpkin, Brittany Sandoval, Justine C. Rutter, Cyrus Y. Jin, Michelle Y. Wang, Shawn Xu, Anna M. Schmoker, Hakyung Cheong, Brian J. Groendyke, Jun Qi, Eric S. Fischer, Benjamin L. Ebert, Nathanael S. Gray

bioRxiv 2023.10.07.561308; doi: https://doi.org/10.1101/2023.10.07.561308 New Results

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Cheminformatics analysis of multi-target structure-activity landscape of environmental chemicals binding to human endocrine receptors
Shanmuga Priya Baskaran, Ajaya Kumar Sahoo, Nikhil Chivukula, Kishan Kumar, Areejit Samal

bioRxiv 2023.10.06.561266; doi: https://doi.org/10.1101/2023.10.06.561266 New Results

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Design of a low-cost photomodulator for in vivo photoactivation of a mGluR5 inhibitor
Hans C. Ajieren, Andrew G. Fox, Ethan N. Biggs, Gabriel O. Albors, Amadeu Llebaria, Pedro P. Irazoqui

bioRxiv 2023.10.07.561310; doi: https://doi.org/10.1101/2023.10.07.561310 Confirmatory Results

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A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling
Pauline Raynaud, Vinesh Jugnarain, Océane Vaugrente, Amandine Vallet, Thomas Boulo, Camille Gauthier, Asuka Inoue, Nathalie Sibille, Christophe Gauthier, Frédéric Jean-Alphonse, Eric Reiter, Pascale Crépieux, Gilles Bruneau

bioRxiv 2023.08.07.552286; doi: https://doi.org/10.1101/2023.08.07.552286 New Results

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Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch
Annika Balzulat, W. Felix Zhu, Cathrin Flauaus, Victor Hernandez-Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko

bioRxiv 2023.10.05.560997; doi: https://doi.org/10.1101/2023.10.05.560997 New Results

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Pharmacokinetics of Extended-release Buprenorphine (Ethiqa) in Female Yorkshire Swine (Sus scrofa domestica)
Lynlee M. Stevey-Rindenow, Marissa Saenz, Vivian La, Craig Franklin, Ari Aycock-Williams, Patrick T. Fueger

bioRxiv 2023.10.04.560917; doi: https://doi.org/10.1101/2023.10.04.560917 New Results

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Liver-specific glucocorticoid action in alcoholic liver disease: study of glucocorticoid receptor knockout and knockin mice
Yazheng Wang, Hong Lu

bioRxiv 2023.10.04.557166; doi: https://doi.org/10.1101/2023.10.04.557166 New Results

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Pharmacology and Toxicology

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