Physiology

Gain-of-function dynamin-2 mutations linked to centronuclear myopathy impair Ca²⁺-induced exocytosis in human myoblasts
Lucas Bayonés, María José Guerra-Fernández, Fernando Hinostroza, Ximena Báez-Matus, Jacqueline Vásquez-Navarrete, Luciana I. Gallo, Sergio Parra, Agustín D. Martínez, Arlek González-Jamett, Fernando D. Marengo, Ana M. Cárdenas

bioRxiv 2022.08.31.506089; doi: https://doi.org/10.1101/2022.08.31.506089 New Results

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Membrane Retrieval after Immediately Releasable Pool (IRP) Exocytosis is produced by Dynamin-Dependent and Dynamin-Independent Mechanisms
Lucas Bayonés, Mauricio Montenegro, José Moya-Díaz, Samuel Alfonso-Bueno, Luciana I. Gallo, Fernando D. Marengo

bioRxiv 2022.08.31.506099; doi: https://doi.org/10.1101/2022.08.31.506099 New Results

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3D Visualisation of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast
Rohan M Lewis, Harikesan Baskaran, Jools Green, Stanimir Tashev, Eleni Paleologou, Emma M Lofthouse, Jane K Cleal, Anton Page, David S Chatelet, Patricia Goggin, Bram G Sengers

bioRxiv 2022.01.26.477815; doi: https://doi.org/10.1101/2022.01.26.477815 New Results

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Metabolic costs of walking and arm reaching in persons with mild multiple sclerosis
Robert Courter, Enrique Alvarez, Roger Enoka, Alaa Ahmed

bioRxiv 2022.08.31.506034; doi: https://doi.org/10.1101/2022.08.31.506034 New Results

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Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor
Brigitte Jia, Alexander Hasse, Fubiao Shi, Sheila Collins

bioRxiv 2022.08.30.505918; doi: https://doi.org/10.1101/2022.08.30.505918 New Results

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PIP₂ and Ca²⁺ regulation of TMEM16A currents in excised inside-out patches
Maiwase Tembo, Crystal Lara-Santos, Joel C. Rosenbaum, Anne E. Carlson

bioRxiv 2022.08.30.505925; doi: https://doi.org/10.1101/2022.08.30.505925 New Results

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TMEM16A activation for the fast block to polyspermy in the African clawed frog does not require conventional activation of egg PLCs
Kayla M. Komondor, Rachel E. Bainbridge, Katherine G. Sharp, Joel C. Rosenbaum, Anne E. Carlson

bioRxiv 2022.08.30.505853; doi: https://doi.org/10.1101/2022.08.30.505853 New Results

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Cardiac pericytes are necessary for coronary vasculature integrity and cardiomyocyte differentiation
Lauriane Cornuault, François-Xavier Hérion, Paul Rouault, Ninon Foussard, Philippe Alzieu, Candice Chapouly, Alain-Pierre Gadeau, Thierry Couffinhal, Marie-Ange Renault

bioRxiv 2022.08.29.505703; doi: https://doi.org/10.1101/2022.08.29.505703 New Results

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Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment
Carrie B. Wiese, Zoey W. Agle, Peixiang Zhang, Karen Reue

bioRxiv 2022.08.29.505758; doi: https://doi.org/10.1101/2022.08.29.505758 New Results

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X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction
Peixiang Zhang, Joseph J. Munier, Laurent Vergnes, Carrie B. Wiese, Jenny C. Link, Fahim Abbasi, Emilio Ronquillo, Antonio Muñoz, Yu-Lin Kuang, Meng Liu, Gabriela Sanchez, Akinyemi Oni-Orisan, Carlos Iribarren, Michael J. McPhaul, Daniel K. Nomura, Joshua W. Knowles, Ronald M. Krauss, Marisa W. Medina, Karen Reue

bioRxiv 2022.08.29.505759; doi: https://doi.org/10.1101/2022.08.29.505759 New Results

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Physiology

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