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Synthetic Biology

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  • EasyGuide plasmids support in vivo assembly of gRNAs for CRISPR/Cas9 applications in Saccharomyces cerevisiae
    Ana P. Jacobus, Joneclei A. Barreto, Lucas S. de Bem, Yasmine A. Menegon, Ícaro Fier, João G.R. Bueno, Leandro V. dos Santos, Jeferson Gross
    bioRxiv 2022.07.01.498453; doi: https://doi.org/10.1101/2022.07.01.498453 New Results
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  • A modular dCas9-based recruitment platform for combinatorial epigenome editing
    Tessa Swain, Christian Pflueger, Saskia Freytag, Daniel Poppe, Jahnvi Pflueger, Trung Nguyen, Ji Kevin Li, Ryan Lister
    bioRxiv 2022.07.01.498378; doi: https://doi.org/10.1101/2022.07.01.498378 New Results
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  • CRISPRi-based circuits for genetic computation in plants
    Muhammad Adil Khan, Gabrielle Herring, Marina Oliva, Elliott Fourie, Jia Yuan Zhu, Benjamin Johnston, Jahnvi Pflüger, Tessa Swain, Christian Pflüger, James Lloyd, David Secco, Ian Small, Brendan Kidd, Ryan Lister
    bioRxiv 2022.07.01.498372; doi: https://doi.org/10.1101/2022.07.01.498372 New Results
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  • ICOR: Improving codon optimization with recurrent neural networks
    Rishab Jain, Aditya Jain, Elizabeth Mauro, Kevin LeShane, Douglas Densmore
    bioRxiv 2021.11.08.467706; doi: https://doi.org/10.1101/2021.11.08.467706 New Results
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  • Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization
    Sijie Zhou, Yi Wu, Yu Zhao, Zhen Zhang, Limin Jiang, Lin Liu, Yan Zhang, Jijun Tang, Ying-Jin Yuan
    bioRxiv 2021.07.19.453002; doi: https://doi.org/10.1101/2021.07.19.453002 New Results
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  • Success probability of high-affinity DNA aptamer generation by genetic alphabet expansion
    Michiko Kimoto, Hui Pen Tan, Yaw Sing Tan, Nur Afiqah Binte Mohd Mislan, Ichiro Hirao
    bioRxiv 2022.06.27.497860; doi: https://doi.org/10.1101/2022.06.27.497860 New Results
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  • Coupling cell communication and optogenetics: Implementation of a light-inducible intercellular system in yeast
    Vicente Rojas, Luis F. Larrondo
    bioRxiv 2022.06.25.497625; doi: https://doi.org/10.1101/2022.06.25.497625 New Results
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  • Antiviral T-cell Biofactory platform for SARS-CoV-2
    Marvin A. Ssemadaali, Sherri Newmyer, Harikrishnan Radhakrishnan, Juan Arredondo, Harold S. Javitz, Satya Dandekar, Parijat Bhatnagar
    bioRxiv 2022.06.26.497669; doi: https://doi.org/10.1101/2022.06.26.497669 New Results
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  • Direct encapsulation of biomolecules in semi-permeable microcapsules produced with double-emulsions
    Grégoire Michielin, Sebastian J. Maerkl
    bioRxiv 2022.06.23.497329; doi: https://doi.org/10.1101/2022.06.23.497329 New Results
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  • Antigen-dependent inducible T cell reporter system for PET imaging of breast cancer and glioblastoma
    Jaehoon Shin, Matthew F. L. Parker, Iowis Zhu, Aryn Alanizi, Carlos I. Rodriguez, Raymond Liu, Payal B. Watchmaker, Mausam Kalita, Joseph Blecha, Justin Luu, Brian Wright, Suzanne E. Lapi, Robert R. Flavell, Hideho Okada, Thea D. Tlsty, Kole T. Roybal, David M. Wilson
    bioRxiv 2022.02.16.480729; doi: https://doi.org/10.1101/2022.02.16.480729 New Results
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