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Synthetic Biology

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  • Discovery and engineering of hypercompact epigenetic modulators for durable gene activation
    Giovanni A Carosso, Robin W Yeo, T.Blair Gainous, Zaki Jawaid, Xiao Yang, Vincent Cutillas, Lei Stanley Qi, Timothy P Daley, Daniel O Hart
    bioRxiv 2023.06.02.543492; doi: https://doi.org/10.1101/2023.06.02.543492 New Results
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  • Rewiring Saccharomyces cerevisiae metabolism for optimised Taxol® precursors production
    Behnaz Nowrouzi, Pablo Torres-Montero, Eduard J. Kerkhoven, José L. Martínez, Leonardo Rios-Solis
    bioRxiv 2023.06.03.543533; doi: https://doi.org/10.1101/2023.06.03.543533 New Results
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  • Autotrophic growth of E. coli is achieved by a small number of genetic changes
    Roee Ben-Nissan, Eliya Milshtein, Vanessa Pahl, Benoit de Pins, Ghil Jona, Dikla Levi, Hadas Yung, Noga Nir, Dolev Ezra, Shmuel Gleizer, Hannes Link, Elad Noor, Ron Milo
    bioRxiv 2023.06.03.543535; doi: https://doi.org/10.1101/2023.06.03.543535 New Results
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  • Calcium-triggered DNA-mediated membrane fusion in synthetic cells
    Yen-Yu Hsu, J. Chen Samuel, Julio Bernal-Chanchavac, Bineet Sharma, Hossein Moghimianavval, Nicholas Stephanopoulos, Allen P. Liu
    bioRxiv 2023.05.06.539684; doi: https://doi.org/10.1101/2023.05.06.539684 New Results
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  • Elucidating the mechanism of microbial thermogenesis
    Puneet Singh Dhatt, Tae Seok Moon
    bioRxiv 2023.06.02.543367; doi: https://doi.org/10.1101/2023.06.02.543367 New Results
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  • Defined synthetic microbial communities colonize and benefit field-grown sorghum
    Citlali Fonseca-García, Andrew Wilson, Joshua Elmore, Dean Pettinga, Ryan McClure, Jackie Atim, Julie Pedraza, Robert Hutmacher, Robert Egbert, Devin Coleman-Derr
    bioRxiv 2023.05.30.542977; doi: https://doi.org/10.1101/2023.05.30.542977 New Results
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  • Metagenomic domain substitution for the high-throughput modification of non-ribosomal peptide analogues
    Sarah R. Messenger, Edward M. R. McGuinniety, Luke J. Stevenson, Jeremy G. Owen, Gregory L. Challis, David F. Ackerley, Mark J. Calcott
    bioRxiv 2023.05.31.543161; doi: https://doi.org/10.1101/2023.05.31.543161 New Results
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  • Spatial Organization of Gas Vesicles is Governed by Phase-separable GvpU
    Zongru Li, Qionghua Shen, Yifan Dai, Andrew P. Anderson, Manuel Iburg, Richard Lin, Brandon Zimmer, Matthew D. Meyer, Lingchong You, Ashutosh Chilkoti, George J. Lu
    bioRxiv 2023.06.01.543273; doi: https://doi.org/10.1101/2023.06.01.543273 New Results
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  • Tuning methylation-dependent silencing dynamics by synthetic modulation of CpG density
    Yitong Ma, Mark W. Budde, Junqin Zhu, Michael B. Elowitz
    bioRxiv 2023.05.30.542205; doi: https://doi.org/10.1101/2023.05.30.542205 New Results
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  • Fundamental trade-off between speed of switching and robustness of genetic switches limits dynamic control of metabolism
    Kaushik Raj, William T. Z. Wong, Beini Zhang, Radhakrishnan Mahadevan
    bioRxiv 2022.03.31.486579; doi: https://doi.org/10.1101/2022.03.31.486579 New Results
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