Synthetic Biology

The impact of chromatin dynamics on Cas9-mediated genome editing in human cells
René M. Daer, Josh P. Cutts, David A. Brafman, Karmella A. Haynes

bioRxiv 071464; doi: https://doi.org/10.1101/071464

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Prototyping of Bacillus megaterium genetic elements through automated cell-free characterization and Bayesian modelling
Simon J. Moore, James T. MacDonald, Sarah Weinecke, Nicolas Kylilis, Karen M. Polizzi, Rebekka Biedendieck, Paul S. Freemont

bioRxiv 071100; doi: https://doi.org/10.1101/071100

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An Analytic framework for stochastic binary biological switches
Guilherme C.P. Innocentini, Sarah Guiziou, Jerome Bonnet, Ovidiu Radulescu

bioRxiv 068759; doi: https://doi.org/10.1101/068759

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Measurements of translation initiation from all 64 codons in E. coli
Ariel Hecht, Jeff Glasgow, Paul R. Jaschke, Lukmaan Bawazer, Matthew S. Munson, Jennifer Cochran, Drew Endy, Marc Salit

bioRxiv 063800; doi: https://doi.org/10.1101/063800

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The role of single occupancy effects on integrase dynamics in a cell-free system
Georgios Artavanis, Victoria Hsiao, Clarmyra A. Hayes, Richard M. Murray

bioRxiv 059675; doi: https://doi.org/10.1101/059675

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Precise Cas9 targeting enables genomic mutation prevention
Alejandro Chavez, Benjamin W Pruitt, Marcelle Tuttle, Rebecca S Shapiro, Ryan J Cecchi, Jordan Winston, Brian M Turczyk, Michael Tung, James J Collins, George M Church

bioRxiv 058974; doi: https://doi.org/10.1101/058974

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Modular non-repeating codes for DNA storage
Ian Holmes

bioRxiv 057448; doi: https://doi.org/10.1101/057448

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Daisy-chain gene drives for the alteration of local populations
Charleston Noble, John Min, Jason Olejarz, Joanna Buchthal, Alejandro Chavez, Andrea L. Smidler, Erika A. DeBenedictis, George M. Church, Martin A. Nowak, Kevin M. Esvelt

bioRxiv 057307; doi: https://doi.org/10.1101/057307

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Evolutionary dynamics of CRISPR gene drives
Charleston Noble, Jason Olejarz, Kevin M. Esvelt, George M. Church, Martin A. Nowak

bioRxiv 057281; doi: https://doi.org/10.1101/057281

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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator
Alexandra M. Westbrook, Julius B. Lucks

bioRxiv 055327; doi: https://doi.org/10.1101/055327

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Synthetic Biology

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