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Synthetic Biology

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  • Millstone: Software for Multiplex Microbial Genome Analysis and Engineering
    Daniel B. Goodman, Gleb Kuznetsov, Marc J. Lajoie, Brian W. Ahern, Michael G. Napolitano, Kevin Y. Chen, Changping Chen, George M. Church
    bioRxiv 086868; doi: https://doi.org/10.1101/086868
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  • Optimizing complex phenotypes through model-guided multiplex genome engineering
    Gleb Kuznetsov, Daniel B. Goodman, Gabriel T. Filsinger, Matthieu Landon, Nadin Rohland, John Aach, Marc J. Lajoie, George M. Church
    bioRxiv 086595; doi: https://doi.org/10.1101/086595
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  • Engineered Cpf1 Enzymes with Altered PAM Specificities
    Linyi Gao, David B.T. Cox, Winston X. Yan, John Manteiga, Martin Schneider, Takashi Yamano, Hiroshi Nishimasu, Osamu Nureki, Feng Zhang
    bioRxiv 091611; doi: https://doi.org/10.1101/091611
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  • DNA Fountain enables a robust and efficient storage architecture
    Yaniv Erlich, Dina Zielinski
    bioRxiv 074237; doi: https://doi.org/10.1101/074237
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  • Prototyping a valinomycin biosynthesis pathway within a cell-free transcription-translation (TX-TL) system
    Tiffany Zhou
    bioRxiv 091520; doi: https://doi.org/10.1101/091520
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  • Rapidly evolving homing CRISPR barcodes
    Reza Kalhor, Prashant Mali, George M. Church
    bioRxiv 055863; doi: https://doi.org/10.1101/055863
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  • The Effect of Compositional Context on Synthetic Gene Networks
    Enoch Yeung, Aaron J. Dy, Kyle B. Martin, Andrew H. Ng, Domitilla Del Vecchio, James L. Beck, James J. Collins, Richard M. Murray
    bioRxiv 083329; doi: https://doi.org/10.1101/083329
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  • Retargeting: an unrecognized consideration in endonuclease-based gene drive biology
    Andrew M. Scharenberg, Barry L Stoddard, Raymond J Monnat, Anthony Nolan
    bioRxiv 089946; doi: https://doi.org/10.1101/089946
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  • Heat-stable preservation of protein expression systems for portable therapeutics production
    David Karig, Seneca Bessling, Peter Thielen, Sherry Zhang, Joshua Wolfe
    bioRxiv 089664; doi: https://doi.org/10.1101/089664
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  • Logic Synthesis of Recombinase-Based Genetic Circuits
    Tai-Yin Chiu, Jie-Hong R. Jiang
    bioRxiv 088930; doi: https://doi.org/10.1101/088930
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