Synthetic Biology

A facile platform to engineer E. coli tyrosyl-tRNA synthetase adds new chemistries to the eukaryotic genetic code, including a phosphotyrosine mimic
Katherine T. Grasso, Soumya Jyoti Singha Roy, Megan Jin Rae Yeo, Chintan Soni, Arianna O. Osgood, Christen M. Hillenbrand, Abhishek Chatterjee

bioRxiv 2021.11.28.470256; doi: https://doi.org/10.1101/2021.11.28.470256 New Results

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Directed evolution of colE1 plasmid replication compatibility: a fast tractable tunable model for investigating biological orthogonality
Santiago Chaillou, Eleftheria-Pinelopi Stamou, Leticia Torres, Ana B. Riesco, Warren Hazelton, Vitor B. Pinheiro

bioRxiv 2021.11.25.470029; doi: https://doi.org/10.1101/2021.11.25.470029 New Results

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ICOR: Improving codon optimization with recurrent neural networks
Rishab Jain, Aditya Jain, Elizabeth Mauro, Kevin LeShane, Douglas Densmore

bioRxiv 2021.11.08.467706; doi: https://doi.org/10.1101/2021.11.08.467706 New Results

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Thermodynamic Constraints on Electromicrobial Protein Production
Lucas Wise, Sabrina Marecos, Katie Randolph, Eric Nshimyumukiza, Mohamed Hassan, Jacob Strouse, Farshid Salimijazi, Buz Barstow

bioRxiv 2021.11.22.469619; doi: https://doi.org/10.1101/2021.11.22.469619 New Results

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Re-introduction of endogenous pathways for propionyl-CoA, 1-propanol and propionate formation in Escherichia coli
Thai Le

bioRxiv 2021.11.21.469472; doi: https://doi.org/10.1101/2021.11.21.469472 New Results

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A protein microarray-based in vitro transglutaminase assay platform for epitope mapping and peptide discovery: implication for transglutaminase-mediated immunodominant determination
Chen Liu

bioRxiv 2021.05.12.443622; doi: https://doi.org/10.1101/2021.05.12.443622 New Results

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Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs
L.-F. Wu, Z. Liu, S. J. Roberts, M. Su, J. W. Szostak, J. D. Sutherland

bioRxiv 2021.11.19.469337; doi: https://doi.org/10.1101/2021.11.19.469337 New Results

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From sequence to yield: deep learning for protein production systems
Evangelos-Marios Nikolados, Oisin Mac Aodha, Guillaume Cambray, Diego A. Oyarzún

bioRxiv 2021.11.18.468948; doi: https://doi.org/10.1101/2021.11.18.468948 New Results

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The Functional Nanopore Screen: A Versatile High-throughput Assay to Study and Engineer Protein Nanopores in Escherichia coli
Wadim Weber, Markus Roeder, Tobias Probanowski, Jie Yang, Helal Abujubara, Heinz Koeppl, Alesia Tietze, Viktor Stein

bioRxiv 2021.04.20.440580; doi: https://doi.org/10.1101/2021.04.20.440580 New Results

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Activating silent glycolysis bypasses in Escherichia coli
Camillo Iacometti, Katharina Marx, Maria Hönick, Viktoria Biletskaia, Helena Schulz-Mirbach, Ari Satanowski, Beau Dronsella, Valérie A. Delmas, Anne Berger, Ivan Dubois, Madeleine Bouzon, Volker Döring, Elad Noor, Arren Bar-Even, Steffen N. Lindner

bioRxiv 2021.11.18.468982; doi: https://doi.org/10.1101/2021.11.18.468982 New Results

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Synthetic Biology

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