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Synthetic Biology

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  • Precise Cas9 targeting enables genomic mutation prevention
    Alejandro Chavez, Benjamin W Pruitt, Marcelle Tuttle, Rebecca S Shapiro, Ryan J Cecchi, Jordan Winston, Brian M Turczyk, Michael Tung, James J Collins, George M Church
    bioRxiv 058974; doi: https://doi.org/10.1101/058974
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  • Modular non-repeating codes for DNA storage
    Ian Holmes
    bioRxiv 057448; doi: https://doi.org/10.1101/057448
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  • Daisy-chain gene drives for the alteration of local populations
    Charleston Noble, John Min, Jason Olejarz, Joanna Buchthal, Alejandro Chavez, Andrea L. Smidler, Erika A. DeBenedictis, George M. Church, Martin A. Nowak, Kevin M. Esvelt
    bioRxiv 057307; doi: https://doi.org/10.1101/057307
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  • Evolutionary dynamics of CRISPR gene drives
    Charleston Noble, Jason Olejarz, Kevin M. Esvelt, George M. Church, Martin A. Nowak
    bioRxiv 057281; doi: https://doi.org/10.1101/057281
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  • Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator
    Alexandra M. Westbrook, Julius B. Lucks
    bioRxiv 055327; doi: https://doi.org/10.1101/055327
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  • Continuous Genetic Recording with Self-Targeting CRISPR-Cas in Human Cells
    Samuel D. Perli, Cheryl H. Cui, Timothy K. Lu
    bioRxiv 053058; doi: https://doi.org/10.1101/053058
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  • Synthetic lipid-containing scaffolds enhance production by co-localizing enzymes
    Cameron Myhrvold, Jessica K. Polka, Pamela A. Silver
    bioRxiv 052035; doi: https://doi.org/10.1101/052035
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  • Development of prokaryotic cell-free systems for synthetic biology
    Abel C. Chiao, Richard M. Murray, Zachary Z Sun
    bioRxiv 048710; doi: https://doi.org/10.1101/048710
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  • GreA and GreB enhance Escherichia coli RNA polymerase transcription rate in a reconstituted transcription-translation system
    Lea L. de Maddalena, Henrike Niederholtmeyer, Matti Turtola, Zoe N. Swank, Georgiy A. Belogurov, Sebastian J. Maerkl
    bioRxiv 024604; doi: https://doi.org/10.1101/024604
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  • Design of a Toolbox of RNA Thermometers
    Shaunak Sen, Divyansh Apurva, Rohit Satija, Dan Siegal, Richard M Murray
    bioRxiv 017269; doi: https://doi.org/10.1101/017269
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