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Synthetic Biology

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  • Expanding the toolbox for phycobiliprotein assembly: phycoerythrobilin biosynthesis in Synechocystis
    Steffen Heck, Frederik Sommer, Susanne Zehner, Michael Schroda, Michelle M. Gehringer, Nicole Frankenberg-Dinkel
    bioRxiv 2023.09.18.558311; doi: https://doi.org/10.1101/2023.09.18.558311 New Results
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  • Genome engineering by RNA-guided transposition for Anabaena PCC 7120
    Sergio Arévalo, Daniel Pérez Rico, Dolores Abarca, Laura W. Dijkhuizen, Cristina Sarasa-Buisan, Peter Lindblad, Enrique Flores, Sandra Nierzwicki-Bauer, Henriette Schluepmann
    bioRxiv 2022.09.18.508393; doi: https://doi.org/10.1101/2022.09.18.508393 New Results
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  • Using the E. coli Alleleome in Strain Design
    PV Phaneuf, ZD Jarczynska, V Kandasamy, SM Chauhan, AM Feist, BO Palsson
    bioRxiv 2023.09.17.558058; doi: https://doi.org/10.1101/2023.09.17.558058 New Results
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  • A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria
    Justin M. Vento, Deniz Durmusoglu, Tianyu Li, Sean Sullivan, Fani Ttofali, John van Schaik, Yanying Yu, Lars Barquist, Nathan Crook, Chase L. Beisel
    bioRxiv 2023.09.16.557782; doi: https://doi.org/10.1101/2023.09.16.557782 New Results
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  • Leucine zipper-based sorting system enables generation of multi-functional CAR T cells
    Scott E. James, Sophia Chen, Brandon D. Ng, Jacob S. Fischman, Lorenz Jahn, Alexander P. Boardman, Adhithi Rajagopalan, Harold K. Elias, Alyssa Massa, Dylan Manuele, Katherine B. Nichols, Amina Lazrak, Nicole Lee, Teng Fei, Susan DeWolf, Jonathan U. Peled, Santosha A. Vardhana, Christopher A. Klebanoff, Marcel R. M. van den Brink
    bioRxiv 2023.09.13.557232; doi: https://doi.org/10.1101/2023.09.13.557232 New Results
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  • IMPROVING ANTIBODY AFFINITY USING LABORATORY DATA WITH LANGUAGE MODEL GUIDED DESIGN
    Ben Krause, Subu Subramanian, Tom Yuan, Marisa Yang, Aaron Sato, Nikhil Naik
    bioRxiv 2023.09.13.557505; doi: https://doi.org/10.1101/2023.09.13.557505 New Results
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  • High-throughput feedback-enabled optogenetic stimulation and spectroscopy in microwell plates
    William Benman, Saachi Datta, David Gonzalez-Martinez, Gloria Lee, Juliette Hooper, Grace Qian, Gabrielle Leavitt, Lana Salloum, Gabrielle Ho, Sharvari Mhatre, Michael S. Magaraci, Michael Patterson, Sevile G. Mannickarottu, Saurabh Malani, Jose L. Avalos, Brian Y. Chow, Lukasz J. Bugaj
    bioRxiv 2022.07.13.499906; doi: https://doi.org/10.1101/2022.07.13.499906 New Results
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  • Manufacturing DNA in E. coli yields higher fidelity DNA than in vitro enzymatic synthesis
    Steven J. Hersch, Siddarth Chandrasekaran, Jamie Lam, Nafiseh Nafissi, Roderick A. Slavcev
    bioRxiv 2023.09.12.557453; doi: https://doi.org/10.1101/2023.09.12.557453 New Results
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  • Targeted Transcriptional Activation using a CRISPR-Associated Transposon System
    Andrea M. Garza Elizondo, James Chappell
    bioRxiv 2023.09.12.557412; doi: https://doi.org/10.1101/2023.09.12.557412 New Results
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  • Passivating blunt-ended helices to control monodispersity and multi-subunit assembly of DNA origami structures
    Jonathan F. Berengut, Willi R. Berg, Felix J. Rizzuto, Lawrence K. Lee
    bioRxiv 2023.09.09.557003; doi: https://doi.org/10.1101/2023.09.09.557003 New Results
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