Synthetic Biology

“Cheater” particles render the VEGAS platform unsuitable for mammalian directed evolution
Christopher E. Denes, Alexander J. Cole, Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Alex W. Hewitt, Daniel Hesselson, G. Gregory Neely

bioRxiv 2022.06.07.495067; doi: https://doi.org/10.1101/2022.06.07.495067 Contradictory Results

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Optimization for Predictive Gene Circuit Design Automation
Frederick Starkey, Filippo Menolascina

bioRxiv 2022.06.21.497000; doi: https://doi.org/10.1101/2022.06.21.497000 New Results

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Engineered gene circuits capable of reinforcement learning allow bacteria to master gameplaying
Adrian Racovita, Satya Prakash, Clenira Varela, Mark Walsh, Roberto Galizi, Mark Isalan, Alfonso Jaramillo

bioRxiv 2022.04.22.489191; doi: https://doi.org/10.1101/2022.04.22.489191 New Results

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Rapid, scalable, combinatorial genome engineering by Marker-less Enrichment and Recombination of Genetically Engineered loci (MERGE)
Mudabir Abdullah, Brittany M. Greco, Jon M. Laurent, Michelle Vandeloo, Edward M. Marcotte, Aashiq H. Kachroo

bioRxiv 2022.06.17.496490; doi: https://doi.org/10.1101/2022.06.17.496490 New Results

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Fine-tuning of coumaric acid synthesis to increase naringenin production in yeast
Jiwei Mao, Marta Tous Mohedano, Xiaowei Li, Quanli Liu, Jens Nielsen, Verena Siewers, Yun Chen

bioRxiv 2022.06.20.496858; doi: https://doi.org/10.1101/2022.06.20.496858 New Results

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Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control
Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh, Lea Wenting Rysavy, Skyler P. Rietberg, Eva L. de la Serna, Guillermo Nicolas Dalton, Dorota Klysz, Evan W. Weber, Won-Ju Kim, Peng Xu, Elena Sotillo, Alexander R. Dunn, Crystal L. Mackall, Robbie G. Majzner

bioRxiv 2022.06.17.496457; doi: https://doi.org/10.1101/2022.06.17.496457 New Results

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Engineered protein nanocages for concurrent RNA and protein packaging in vivo
Seokmu Kwon, Tobias W. Giessen

bioRxiv 2022.06.16.496435; doi: https://doi.org/10.1101/2022.06.16.496435 New Results

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Tunable control of insect pheromone biosynthesis in Nicotiana benthamiana
Kalyani Kallam, Elena Moreno-Giménez, Ruben Mateos-Fernández, Connor Tansley, Silvia Gianoglio, Diego Orzaez, Nicola J. Patron

bioRxiv 2022.06.15.496242; doi: https://doi.org/10.1101/2022.06.15.496242 New Results

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Building an RNA switch-based selection system for enzyme evolution in yeast
Deze Kong, Christina Smolke

bioRxiv 2022.06.14.496130; doi: https://doi.org/10.1101/2022.06.14.496130 New Results

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Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback
Joaquín Gutiérrez, Sant Kumar, Mustafa Khammash

bioRxiv 2022.06.13.495893; doi: https://doi.org/10.1101/2022.06.13.495893 New Results

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Synthetic Biology

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