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Synthetic Biology

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  • Engineering a functional NifDK polyprotein resistant to mitochondrial degradation
    Rob Allen, Christina Gregg, Shoko Okada, Amratha Menon, Dawar Hussain, Vanessa Gillespie, Ema Johnston, Andrew Warden, Matthew Taylor, Michelle Colgrave, Keren Byrne, Craig Wood
    bioRxiv 755116; doi: https://doi.org/10.1101/755116 New Results
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  • Proteolytic queues at ClpXP increase antibiotic tolerance
    Heather S. Deter, Alawiah H. Abualrahi, Prajakta Jadhav, Elise K. Schweer, Curtis T. Ogle, Nicholas C. Butzin
    bioRxiv 680504; doi: https://doi.org/10.1101/680504 New Results
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  • Rapid and assured genetic engineering methods applied to Acinetobacter baylyi ADP1 genome streamlining
    Gabriel A. Suárez, Kyle R. Dugan, Brian A. Renda, Sean P. Leonard, Lakshmi S. Gangavarapu, Jeffrey E. Barrick
    bioRxiv 754242; doi: https://doi.org/10.1101/754242 New Results
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  • Large scale active-learning-guided exploration to maximize cell-free production
    Olivier Borkowski, Mathilde Koch, Agnès Zettor, Amir Pandi, Angelo Cardoso Batista, Paul Soudier, Jean-Loup Faulon
    bioRxiv 751669; doi: https://doi.org/10.1101/751669 New Results
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  • High-performance chemical and light-inducible recombinases in mammalian cells and mice
    Benjamin H. Weinberg, Jang Hwan Cho, Yash Agarwal, N. T. Hang Pham, Leidy D. Caraballo, Maciej Walkosz, Charina Ortega, Micaela Trexler, Nathan Tague, Billy Law, William K. J. Benman, Justin Letendre, Jacob Beal, Wilson W. Wong
    bioRxiv 747121; doi: https://doi.org/10.1101/747121 New Results
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  • Robust characterization of two distinct glutarate sensing transcription factors of Pseudomonas putida L-lysine metabolism
    Mitchell G. Thompson, Zak Costello, Niklas F. C. Hummel, Pablo Cruz-Morales, Jacquelyn M. Blake-Hedges, Rohith N. Krishna, Will Skyrud, Allison N. Pearson, Matthew R. Incha, Patrick M. Shih, Hector Garcia-Martin, Jay D. Keasling
    bioRxiv 557751; doi: https://doi.org/10.1101/557751 New Results
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  • Harnessing natural modularity of cellular metabolism to design a modular chassis cell for a diverse class of products by using goal attainment optimization
    Sergio Garcia, Cong T. Trinh
    bioRxiv 748350; doi: https://doi.org/10.1101/748350 New Results
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  • Universal Loop assembly (uLoop): open, efficient, and species-agnostic DNA fabrication
    Bernardo Pollak, Tamara Matute, Isaac Nuñez, Ariel Cerda, Constanza Lopez, Valentina Vargas, Anton Kan, Vincent Bielinski, Peter von Dassow, Chris L. Dupont, Fernán Federici
    bioRxiv 744854; doi: https://doi.org/10.1101/744854 New Results
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  • Multidimensional Data Organization and Random Access in Large-Scale DNA Storage Systems
    Xin Song, Shalin Shah, John Reif
    bioRxiv 743369; doi: https://doi.org/10.1101/743369 New Results
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  • Simplified Methodology for a Modular and Genetically Expanded Protein Synthesis in Cell-Free Systems
    Yonatan Chemla, Eden Ozer, Michael Shaferman, Ben Zaad, Rambabu Dandela, Lital Alfonta
    bioRxiv 742726; doi: https://doi.org/10.1101/742726 New Results
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