Systems Biology

Inferring TF activities and activity regulators from gene expression data with constraints from TF perturbation data
Cynthia Ma, Michael R. Brent

bioRxiv 2020.05.25.108654; doi: https://doi.org/10.1101/2020.05.25.108654 New Results

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Autism genetics perturb prenatal neurodevelopment through a hierarchy of broadly-expressed and brain-specific genes
Vahid H. Gazestani, Austin WT Chiang, Eric Courchesne, Nathan E. Lewis

bioRxiv 2020.05.23.112623; doi: https://doi.org/10.1101/2020.05.23.112623 New Results

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Simulating single-cell metabolism using a stochastic flux-balance analysis algorithm
David S. Tourigny, Arthur P. Goldberg, Jonathan R. Karr

bioRxiv 2020.05.22.110577; doi: https://doi.org/10.1101/2020.05.22.110577 New Results

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What influences selection of native phosphorelay architectures?
Rui Alves, Baldiri Salvado, Ron Milo, Ester Vilaprinyo, Albert Sorribas

bioRxiv 2020.05.21.108001; doi: https://doi.org/10.1101/2020.05.21.108001 New Results

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Reliable identification of protein-protein interactions by crosslinking mass spectrometry
Swantje Lenz, Ludwig R. Sinn, Francis J. O’Reilly, Lutz Fischer, Fritz Wegner, Juri Rappsilber

bioRxiv 2020.05.25.114256; doi: https://doi.org/10.1101/2020.05.25.114256 New Results

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Rolling Signal-based Ripley’s K: A new algorithm to identify spatial patterns in histological specimens
Connor P. Healy, Frederick R. Adler, Tara L. Deans

bioRxiv 2020.05.21.109314; doi: https://doi.org/10.1101/2020.05.21.109314 New Results

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Biophysical modeling of the SARS-CoV-2 viral cycle reveals ideal antiviral targets
Brian T. Castle, Carissa Dock, Mahya Hemmat, Susan Kline, Christopher Tignanelli, Radha Rajasingham, David Masopust, Paolo Provenzano, Ryan Langlois, Timothy Schacker, Ashley Haase, David J. Odde

bioRxiv 2020.05.22.111237; doi: https://doi.org/10.1101/2020.05.22.111237 New Results

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The specificity of SRC Homology 3 (SH3) domain interactions is modulated by their protein context in vivo
Ugo Dionne, Émilie Bourgault, Alexandre K Dubé, David Bradley, François Chartier, Rohan Dandage, Soham Dibyachintan, Philippe C Després, Gerald D Gish, Jean-Philippe Lambert, Nicolas Bisson, Christian R Landry

bioRxiv 2020.05.18.103002; doi: https://doi.org/10.1101/2020.05.18.103002 New Results

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A clinically validated human capillary blood transcriptome test for global systems biology studies
Ryan Toma, Ben Pelle, Nathan Duval, Matthew M Parks, Vishakh Gopu, Hal Tily, Andrew Hatch, Ally Perlina, Guruduth Banavar, Momchilo Vuyisich

bioRxiv 2020.05.22.110080; doi: https://doi.org/10.1101/2020.05.22.110080 New Results

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Reconstruction of Fur pan-regulon uncovers the complexity and diversity of transcriptional regulation in E. coli
Ye Gao, Ina Bang, Yara Seif, Gayoung Nam, Anand V. Sastry, Ke Chen, Jonathan M. Monk, Kumari Sonal Choudhary, Sang Woo Seo, Eun-Yeol Lee, Donghyuk Kim, Bernhard O. Palsson

bioRxiv 2020.05.21.109694; doi: https://doi.org/10.1101/2020.05.21.109694 New Results

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Systems Biology

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