Systems Biology

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
Scott C Ritchie, Johannes Kettunen, Marta Brozynska, Artika P Nath, Aki S Havulinna, Satu Männistö, Markus Perola, Veikko Salomaa, Mika Ala-Korpela, Gad Abraham, Peter Würtz, Michael Inouye

bioRxiv 309138; doi: https://doi.org/10.1101/309138 New Results
Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture
SHOURYADIPTA GHOSH, Kenneth Tran, Lea M. D. Delbridge, Anthony J. R. Hickey, Eric Hanssen, Edmund J. Crampin, Vijay Rajagopal

bioRxiv 327254; doi: https://doi.org/10.1101/327254 New Results
Identification of Casiopeina II-gly secondary targets through a systems pharmacology approach
Guillermo de Anda-Jauregui, Jesus Espinal-Enriquez, Junguk Hur, Sergio Antonio Alcalá-Corona, Lena Ruiz-Azuara, Enrique Hernandez-Lemus

bioRxiv 327718; doi: https://doi.org/10.1101/327718 New Results
Causal interactions from proteomic profiles: molecular data meets pathway knowledge
Özgün Babur, Augustin Luna, Anil Korkut, Funda Durupinar, Metin Can Siper, Ugur Dogrusoz, Joseph E. Aslan, Chris Sander, Emek Demir

bioRxiv 258855; doi: https://doi.org/10.1101/258855 New Results
SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework
Benjamin J Sanchez, Feiran Li, Eduard J Kerkhoven, Jens Nielsen

bioRxiv 324863; doi: https://doi.org/10.1101/324863 New Results
NECorr, a Tool to Rank Gene Importance in Biological Processes using Molecular Networks and Transcriptome Data
Christophe Victor Liseron-Monfils, Andrew Olson, Doreen Ware

bioRxiv 326868; doi: https://doi.org/10.1101/326868 New Results
Reconstruction of consensus tissue-specific metabolic models
Sara Correia, Bruno Costa, Miguel Rocha

bioRxiv 327262; doi: https://doi.org/10.1101/327262 New Results
Model-driven design and evolution of non-trivial synthetic syntrophic pairs
Colton Joseph Lloyd, Zachary King, Troy Sandberg, Ying Hefner, Connor Olson, Patrick Phaneuf, Edward O'Brien, Adam Feist

bioRxiv 327270; doi: https://doi.org/10.1101/327270 New Results
A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases
Jialiang Yang, Bin Zhang, Sander Houten, Eric Schadt, Jun Zhu, Yousin Suh, Zhidong Tu

bioRxiv 326264; doi: https://doi.org/10.1101/326264 New Results
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interaction networks
Scott W Simpkins, Justin Nelson, Raamesh Deshpande, Sheena C Li, Jeff S Piotrowski, Erin H Wilson, Abraham A Gebre, Reika Okamoto, Mami Yoshimura, Michael Costanzo, Yoko Yashiroda, Yoshikazu Ohya, Hiroyuki Osada, Minoru Yoshida, Charles Boone, Chad L Myers

bioRxiv 111252; doi: https://doi.org/10.1101/111252 New Results

Systems Biology

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