Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

Yi-Chieh Wu; Mukul S. Bansal; Matthew D. Rasmussen; Javier Herrero; Manolis Kellis

doi:10.1101/005736

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Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

Yi-Chieh Wu, Mukul S. Bansal, Matthew D. Rasmussen, Javier Herrero, Manolis Kellis

doi: https://doi.org/10.1101/005736

Yi-Chieh Wu

1Department of Electrical Engineering and Computer Science, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 02139

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For correspondence: yjw@mit.edu

Mukul S. Bansal

1Department of Electrical Engineering and Computer Science, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 02139

2Current address: Department of Computer Science and Engineering, University of Connecticut, Storrs, Connecticut, USA 06269

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Matthew D. Rasmussen

3Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA 14850

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Javier Herrero

4European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK

5Current address: Bill Lyons Informatics Centre, UCL Cancer Institute, University College London London WC1E 6BT, UK

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Manolis Kellis

1Department of Electrical Engineering and Computer Science, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 02139

6Broad Institute, Cambridge, Massachusetts, USA 02142