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Reagent contamination can critically impact sequence-based microbiome analyses

Susannah J Salter, Michael J Cox, Elena M Turek, Szymon T Calus, William O Cookson, Miriam F Moffatt, Paul Turner, Julian Parkhill, Nick Loman, Alan W Walker
doi: https://doi.org/10.1101/007187
Susannah J Salter
1Pathogen Genomics Group, Wellcome Trust Sanger Institute, Hinxton, CB10 ISA, UK
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Michael J Cox
2Molecular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, SW3 6LY
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Elena M Turek
2Molecular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, SW3 6LY
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Szymon T Calus
3Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK
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William O Cookson
2Molecular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, SW3 6LY
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Miriam F Moffatt
2Molecular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, SW3 6LY
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Paul Turner
4Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
5Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK
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Julian Parkhill
1Pathogen Genomics Group, Wellcome Trust Sanger Institute, Hinxton, CB10 ISA, UK
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Nick Loman
3Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK
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Alan W Walker
1Pathogen Genomics Group, Wellcome Trust Sanger Institute, Hinxton, CB10 ISA, UK
6Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, AB219SB, UK
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Posted July 16, 2014.
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Reagent contamination can critically impact sequence-based microbiome analyses
Susannah J Salter, Michael J Cox, Elena M Turek, Szymon T Calus, William O Cookson, Miriam F Moffatt, Paul Turner, Julian Parkhill, Nick Loman, Alan W Walker
bioRxiv 007187; doi: https://doi.org/10.1101/007187
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Reagent contamination can critically impact sequence-based microbiome analyses
Susannah J Salter, Michael J Cox, Elena M Turek, Szymon T Calus, William O Cookson, Miriam F Moffatt, Paul Turner, Julian Parkhill, Nick Loman, Alan W Walker
bioRxiv 007187; doi: https://doi.org/10.1101/007187

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