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Glucose-lactate metabolic cooperation in cancer: insights from a spatial mathematical model and implications for targeted therapy

Jessica B. McGillen, Catherine J. Kelly, Alicia Martíez-González, Natasha K. Martin, Eamonn A. Gaffney, Philip K. Maini, Vıctor M. Pérez-García
doi: https://doi.org/10.1101/008839
Jessica B. McGillen
aMathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, United Kingdom
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  • For correspondence: jessica.mcgillen@maths.ox.ac.uk
Catherine J. Kelly
bDepartment of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, United Kingdom
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Alicia Martíez-González
cInstituto de Matemática Aplicada a la Ciencia y la Ingeniería, Universidad de Castilla-La Mancha, Avda. Camilo José Cela, 13071 Ciudad Real, Spain
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Natasha K. Martin
dSchool of Social and Community Medicine, Bristol University, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, United Kingdom
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Eamonn A. Gaffney
aMathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, United Kingdom
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Philip K. Maini
aMathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, United Kingdom
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Vıctor M. Pérez-García
cInstituto de Matemática Aplicada a la Ciencia y la Ingeniería, Universidad de Castilla-La Mancha, Avda. Camilo José Cela, 13071 Ciudad Real, Spain
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Article Information

doi 
https://doi.org/10.1101/008839
History 
  • September 4, 2014.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jessica B. McGillena,*,
  2. Catherine J. Kellyb,
  3. Alicia Martíez-Gonzálezc,
  4. Natasha K. Martind,
  5. Eamonn A. Gaffneya,
  6. Philip K. Mainia and
  7. Vıctor M. Pérez-Garcíac
  1. aMathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, United Kingdom
  2. bDepartment of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, United Kingdom
  3. cInstituto de Matemática Aplicada a la Ciencia y la Ingeniería, Universidad de Castilla-La Mancha, Avda. Camilo José Cela, 13071 Ciudad Real, Spain
  4. dSchool of Social and Community Medicine, Bristol University, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, United Kingdom
  1. ↵*Corresponding author Email addresses: jessica.mcgillen{at}maths.ox.ac.uk (Jessica B. McGillen)
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Posted September 04, 2014.
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Glucose-lactate metabolic cooperation in cancer: insights from a spatial mathematical model and implications for targeted therapy
Jessica B. McGillen, Catherine J. Kelly, Alicia Martíez-González, Natasha K. Martin, Eamonn A. Gaffney, Philip K. Maini, Vıctor M. Pérez-García
bioRxiv 008839; doi: https://doi.org/10.1101/008839
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Glucose-lactate metabolic cooperation in cancer: insights from a spatial mathematical model and implications for targeted therapy
Jessica B. McGillen, Catherine J. Kelly, Alicia Martíez-González, Natasha K. Martin, Eamonn A. Gaffney, Philip K. Maini, Vıctor M. Pérez-García
bioRxiv 008839; doi: https://doi.org/10.1101/008839

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