Abstract
Measuring relative fitness by pairwise competition experiments is laborious and expensive. Accordingly, many investigators estimate fitness from the maximum growth rate during exponential growth. However, maximum growth rates have been shown to be an unreliable measure of fitness as indicated by discrepancies between these parameters and the outcomes of pairwise competition experiments. Here we propose a new method that estimates relative fitness by predicting the results of competition experiments from single strain growth curves.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Posted July 23, 2015.
