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Mapping phylogenetic trees to reveal distinct patterns of evolution

View ORCID ProfileMichelle Kendall, View ORCID ProfileCaroline Colijn
doi: https://doi.org/10.1101/026641
Michelle Kendall
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Abstract

Evolutionary relationships are described by phylogenetic trees, but a central barrier in many fields is the difficulty of interpreting data containing conflicting phylogenetic signals. Obtaining credible trees that capture the relationships present in complex data is one of the fundamental challenges in evolution today. We present a way to map trees which extracts distinct alternative evolutionary relationships embedded in data and re-solves phylogenetic uncertainty. Our method reveals a remarkably distinct phylogenetic signature in the VP30 gene of Ebolavirus, indicating possible recombination with significant implications for vaccine development. Moving to higher organisms, we use our approach to detect alternative histories of the evolution of anole lizards. Our approach has the capacity to resolve key areas of uncertainty in the study of evolution, and to broaden the credibility and appeal of phylogenetic methods.

Footnotes

  • ↵* This work was supported by the Engineering and Physical Sciences Research Council EP/K026003/1

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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Posted September 11, 2015.
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Mapping phylogenetic trees to reveal distinct patterns of evolution
Michelle Kendall, Caroline Colijn
bioRxiv 026641; doi: https://doi.org/10.1101/026641
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Mapping phylogenetic trees to reveal distinct patterns of evolution
Michelle Kendall, Caroline Colijn
bioRxiv 026641; doi: https://doi.org/10.1101/026641

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