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Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively

Andrew R Wood, Jessica Tyrell, Robin Beaumont, Samuel E. Jones, Marcus A. Tuke, Katherine S. Ruth, The GIANT consortium, Hanieh Yaghootkar, Rachel Freathy, Anna Murray, Timothy M. Frayling, Michael N. Weedon
doi: https://doi.org/10.1101/027490
Andrew R Wood
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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  • For correspondence: A.R.Wood@exeter.ac.uk
Jessica Tyrell
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Robin Beaumont
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Samuel E. Jones
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Marcus A. Tuke
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Katherine S. Ruth
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
Hanieh Yaghootkar
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Rachel Freathy
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Anna Murray
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Timothy M. Frayling
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Michael N. Weedon
Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
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Article Information

doi 
https://doi.org/10.1101/027490
History 
  • September 25, 2015.

Article Versions

  • older version (September 24, 2015 - 07:25).
  • You are viewing the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Andrew R Wood*,1,
  2. Jessica Tyrell1,
  3. Robin Beaumont1,
  4. Samuel E. Jones1,
  5. Marcus A. Tuke1,
  6. Katherine S. Ruth1,
  7. The GIANT consortium,
  8. Hanieh Yaghootkar1,
  9. Rachel Freathy1,
  10. Anna Murray1,
  11. Timothy M. Frayling1* and
  12. Michael N. Weedon1*
  1. 1Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK
  1. ↵*Corresponding Author: Andrew Wood: A.R.Wood{at}exeter.ac.uk
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Posted September 25, 2015.
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Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively
Andrew R Wood, Jessica Tyrell, Robin Beaumont, Samuel E. Jones, Marcus A. Tuke, Katherine S. Ruth, The GIANT consortium, Hanieh Yaghootkar, Rachel Freathy, Anna Murray, Timothy M. Frayling, Michael N. Weedon
bioRxiv 027490; doi: https://doi.org/10.1101/027490
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Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively
Andrew R Wood, Jessica Tyrell, Robin Beaumont, Samuel E. Jones, Marcus A. Tuke, Katherine S. Ruth, The GIANT consortium, Hanieh Yaghootkar, Rachel Freathy, Anna Murray, Timothy M. Frayling, Michael N. Weedon
bioRxiv 027490; doi: https://doi.org/10.1101/027490

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