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TP53 copy number expansion correlates with the evolution of increased body size and an enhanced DNA damage response in elephants

Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P. Mongan, Richard D. Emes, View ORCID ProfileVincent J. Lynch
doi: https://doi.org/10.1101/028522
Michael Sulak
1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
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Lindsey Fong
1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
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Katelyn Mika
1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
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Sravanthi Chigurupati
1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
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Lisa Yon
2School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences. University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD. UK.
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Nigel P. Mongan
2School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences. University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD. UK.
3Department of Pharmacology, Weill Cornell Medical College, New York, NY, 10065
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Richard D. Emes
2School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences. University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD. UK.
4Advanced Data Analysis Centre, University of Nottingham UK.
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Vincent J. Lynch
1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
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  • ORCID record for Vincent J. Lynch
  • For correspondence: vjlynch@uchicago.edu
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Article Information

doi 
https://doi.org/10.1101/028522
History 
  • October 6, 2015.

Article Versions

  • You are currently viewing Version 1 of this article (October 6, 2015 - 14:10).
  • Version 2 (November 24, 2015 - 09:41).
  • View Version 3, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Michael Sulak‡1,
  2. Lindsey Fong‡1,
  3. Katelyn Mika1,
  4. Sravanthi Chigurupati1,
  5. Lisa Yon2,
  6. Nigel P. Mongan2,3,
  7. Richard D. Emes2,4 and
  8. Vincent J. Lynch*,1‡
  1. 1Department of Human Genetics, The University of Chicago, Chicago, IL, 60637
  2. 2School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences. University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD. UK.
  3. 3Department of Pharmacology, Weill Cornell Medical College, New York, NY, 10065
  4. 4Advanced Data Analysis Centre, University of Nottingham UK.
  1. ↵* To whom correspondence should be addressed: vjlynch{at}uchicago.edu
  1. ↵‡ Contributed equally

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Posted October 06, 2015.
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TP53 copy number expansion correlates with the evolution of increased body size and an enhanced DNA damage response in elephants
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P. Mongan, Richard D. Emes, Vincent J. Lynch
bioRxiv 028522; doi: https://doi.org/10.1101/028522
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TP53 copy number expansion correlates with the evolution of increased body size and an enhanced DNA damage response in elephants
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P. Mongan, Richard D. Emes, Vincent J. Lynch
bioRxiv 028522; doi: https://doi.org/10.1101/028522

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