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History
- November 12, 2015.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Danesh Saleheen1,2†*,
- Pradeep Natarajan3,4†,
- Wei Zhao1,
- Asif Rasheed2,
- Sumeet Khetarpal5,
- Hong-Hee Won3,4,
- Konrad J. Karczewski4,6,
- Anne H O’Donnell-Luria4,6,7,
- Kaitlin E. Samocha6,
- Namrata Gupta4,
- Mozzam Zaidi2,
- Maria Samuel2,
- Atif Imran2,
- Shahid Abbas8,
- Faisal Majeed2,
- Madiha Ishaq2,
- Saba Akhtar2,
- Kevin Trindade5,
- Megan Mucksavage5,
- Nadeem Qamar9,
- Khan Shah Zaman9,
- Zia Yaqoob9,
- Tahir Saghir9,
- Syed Nadeem Hasan Rizvi9,
- Anis Memon9,
- Nadeem Hayyat Mallick10,
- Mohammad Ishaq11,
- Syed Zahed Rasheed11,
- Fazal-ur-Rehman Memon12,
- Khalid Mahmood13,
- Naveeduddin Ahmed14,
- Ron Do15,16,
- Daniel G. MacArthur4,6,
- Stacey Gabriel4,
- Eric S. Lander4,
- Mark J. Daly4,6,
- Philippe Frossard2†,
- John Danesh17,18†,
- Daniel J. Rader5,19† and
- Sekar Kathiresan3,4†*
- 1Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
- 2Center for Non-Communicable Diseases, Karachi, Pakistan
- 3Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA
- 4Broad Institute of Harvard and MIT, Cambridge, MA, USA
- 5Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
- 6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
- 7Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
- 8Faisalabad Institute of Cardiology, Faisalabad, Pakistan
- 9National Institute of Cardiovascular Disorders, Karachi, Pakistan
- 10Punjab Institute of Cardiology, Lahore, Pakistan
- 11Karachi Institute of Heart Diseases, Karachi, Pakistan
- 12Red Crescent Institute of Cardiology, Hyderabad, Pakistan
- 13The Civil Hospital, Karachi, Pakistan
- 14Liaquat National Hospital, Karachi, Pakistan
- 15Department of Genetics and Genomic Sciences, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA
- 16The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
- 17Department of Public Health and Primary Care, University of Cambridge, UK
- 18Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
- 19Department of Human Genetics, University of Pennsylvania, USA
- ↵*Corresponding authors:
Danish Saleheen, MBBS, PhD Department of Biostatistics and Epidemiology University of Pennsylvania 11–134 Translational Research Center3400 Civic Center Boulevard Philadelphia, PA 19104 Tel: 215–573–6323 Fax: 215–573–2094 Email: saleheen{at}mail.med.upenn.edu Sekar Kathiresan, MD Broad Institute and Massachusetts General Hospital CPZN 5.252 185 Cambridge Street Boston, MA 02114 Tel: 617–643–6120 Email: sekar{at}broadinstitute.org
↵† Contributed equally