Tempo and mode of genome evolution in a 50,000-generation experiment

Olivier Tenaillon; Jeffrey E. Barrick; Noah Ribeck; Daniel E. Deatherage; Jeffrey L. Blanchard; Aurko Dasgupta; Gabriel C. Wu; Sébastien Wielgoss; Stéphane Cruveiller; Claudine Médigue; Dominique Schneider; Richard E. Lenski

doi:10.1101/036806

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Tempo and mode of genome evolution in a 50,000-generation experiment

Olivier Tenaillon, Jeffrey E. Barrick, Noah Ribeck, Daniel E. Deatherage, Jeffrey L. Blanchard, Aurko Dasgupta, Gabriel C. Wu, Sébastien Wielgoss, Stéphane Cruveiller, Claudine Médigue, Dominique Schneider, View ORCID ProfileRichard E. Lenski

doi: https://doi.org/10.1101/036806

Olivier Tenaillon

1Université Paris Diderot, IAME, UMR 1137, Sorbonne Paris Cité, F-75018 Paris, France.

2INSERM, IAME, UMR 1137, F-75018 Paris, France.

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Jeffrey E. Barrick

3Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, TX 78712, USA.

4BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI 48824, USA.

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Noah Ribeck

4BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI 48824, USA.

5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.

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Daniel E. Deatherage

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Jeffrey L. Blanchard

6Department of Biology, University of Massachusetts, Amherst, MA 01003, USA.

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Aurko Dasgupta

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Gabriel C. Wu

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Sébastien Wielgoss

7Institute of Integrative Biology, ETH Zürich, Universitätstrasse 16, Zürich 8092, Switzerland.

8Université Grenoble Alpes, Laboratoire Technologies de l’Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), F-38000 Grenoble, France.

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Stéphane Cruveiller

9Direction des Sciences du Vivant, CEA, Institut de Génomique, Genoscope & CNRS-UMR8030, Évry, France.

10Laboratoire d’Analyses Bioinformatiques en Génomique et Métabolisme, Évry, France.

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Claudine Médigue

9Direction des Sciences du Vivant, CEA, Institut de Génomique, Genoscope & CNRS-UMR8030, Évry, France.

10Laboratoire d’Analyses Bioinformatiques en Génomique et Métabolisme, Évry, France.

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Dominique Schneider

8Université Grenoble Alpes, Laboratoire Technologies de l’Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), F-38000 Grenoble, France.

11Centre National de la Recherche Scientifique, TIMC-IMAG, F-38000 Grenoble, France