MetaXcan: Summary Statistics Based Gene-Level Association Method Infers Accurate PrediXcan Results

Alvaro Barbeira; Kaanan P. Shah; Jason M. Torres; Heather E Wheeler; Eric S. Torstenson; Todd Edwards; Tzintzuni Garcia; Graeme I Bell; Dan Nicolae; Nancy J Cox; Hae Kyung Im

doi:10.1101/045260

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MetaXcan: Summary Statistics Based Gene-Level Association Method Infers Accurate PrediXcan Results

Alvaro Barbeira, Kaanan P. Shah, Jason M. Torres, Heather E Wheeler, Eric S. Torstenson, Todd Edwards, Tzintzuni Garcia, Graeme I Bell, Dan Nicolae, Nancy J Cox, Hae Kyung Im

doi: https://doi.org/10.1101/045260

Alvaro Barbeira

1Department of Physics, Instituto Tecnologico de Buenos Aires, CABA, Argentina

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Kaanan P. Shah

2Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA

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Jason M. Torres

3Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL, USA

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Heather E Wheeler

4Departments of Biology and Computer Science, Loyola University Chicago, Chicago, IL, USA

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Eric S. Torstenson

5Vanderbilt Genetic Institute, Vanderbilt University, Nashville, TN, USA

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Todd Edwards

5Vanderbilt Genetic Institute, Vanderbilt University, Nashville, TN, USA

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Tzintzuni Garcia

6Center for Research Informatics, The University of Chicago, IL, USA

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Graeme I Bell

7Section of Endocrinology, The University of Chicago, Chicago, IL, USA

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Dan Nicolae

1Department of Physics, Instituto Tecnologico de Buenos Aires, CABA, Argentina

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Nancy J Cox

5Vanderbilt Genetic Institute, Vanderbilt University, Nashville, TN, USA

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Hae Kyung Im

2Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA

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Posted March 23, 2016.

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MetaXcan: Summary Statistics Based Gene-Level Association Method Infers Accurate PrediXcan Results

Alvaro Barbeira, Kaanan P. Shah, Jason M. Torres, Heather E Wheeler, Eric S. Torstenson, Todd Edwards, Tzintzuni Garcia, Graeme I Bell, Dan Nicolae, Nancy J Cox, Hae Kyung Im

bioRxiv 045260; doi: https://doi.org/10.1101/045260

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MetaXcan: Summary Statistics Based Gene-Level Association Method Infers Accurate PrediXcan Results

Alvaro Barbeira, Kaanan P. Shah, Jason M. Torres, Heather E Wheeler, Eric S. Torstenson, Todd Edwards, Tzintzuni Garcia, Graeme I Bell, Dan Nicolae, Nancy J Cox, Hae Kyung Im

bioRxiv 045260; doi: https://doi.org/10.1101/045260

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