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History
- March 30, 2016.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Ruzbeh Mosadeghi1,2*,
- Kurt M. Reichermeier2,
- Martin Winkler3,
- Anne Schreiber3,
- Justin M. Reitsma2,
- Yaru Zhang2,
- Florian Stengel4,8,
- Junyue Cao2,
- Minsoo Kim2,
- Michael J. Sweredoski5,
- Sonja Hess5,
- Alexander Leitner4,8,
- Ruedi Aebersold4,6,
- Matthias Peter3,&,
- Raymond J. Deshaies2,7,& and
- Radoslav I. Enchev3*&
- 1Keck School of Medicine of the University of Southern California/California Institute of Technology Combined MD/PhD Program
- 2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena CA, USA, 911250
- 3Department of Biology, Institute of Biochemistry, Swiss Federal Institute of Technology, Otto-Stern Weg 3, 8093 Zürich, Switzerland
- 4Department of Biology, Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, HPT E 78, August-Piccard-Hof 1, 8093 Zürich, Switzerland
- 5Proteome Exploration Lab, Beckman Institute, California Institute of Technology, Pasadena CA, USA, 91125
- 6Faculty of Science, University of Zurich, Zurich, Switzerland
- 7Howard Hughes Medical Institute
- 8Current Address - Department of Biology, University of Konstanz, 78457 Konstanz, Germany
- ↵&corresponding authors
↵* equal contribution
Posted March 30, 2016.
Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
