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Acute induction of anomalous blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (LPS)

Etheresia Pretorius, Sthembile Mbotwa, Janette Bester, Christopher Robinson, Douglas B. Kell
doi: https://doi.org/10.1101/053538
Etheresia Pretorius
1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Arcadia 0007, South Africa
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Sthembile Mbotwa
1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Arcadia 0007, South Africa
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Janette Bester
1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Arcadia 0007, South Africa
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Christopher Robinson
2Faculty of Life Sciences, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
4The Manchester Institute of Biotechnology, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
5Centre for Synthetic Biology of Fine and Speciality Chemicals, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
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Douglas B. Kell
3School of Chemistry, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
4The Manchester Institute of Biotechnology, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
5Centre for Synthetic Biology of Fine and Speciality Chemicals, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
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Article Information

doi 
https://doi.org/10.1101/053538
History 
  • May 16, 2016.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. 1,*Etheresia Pretorius,
  2. 1Sthembile Mbotwa,
  3. 1Janette Bester,
  4. 2,4,5Christopher Robinson and
  5. 3,4,5,*Douglas B. Kell
  1. 1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Arcadia 0007, South Africa
  2. 2Faculty of Life Sciences, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
  3. 3School of Chemistry, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
  4. 4The Manchester Institute of Biotechnology, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
  5. 5Centre for Synthetic Biology of Fine and Speciality Chemicals, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK
  1. ↵*Corresponding authors: Etheresia Pretorius, Department of Physiology, Faculty of Health Sciences, University of Pretoria Private Bag x323, ARCADIA, 0007, SOUTH AFRICA, resia.pretorius@up.ac.za, Tel: (+27)12 420 2864
  2. ↵*Douglas B. Kell, School of Chemistry and The Manchester Institute of Biotechnology, The University of Manchester, 131, Princess St, MANCHESTER M1 7DN, Lancs, UK, dbk@manchester.ac.uk, Tel: (+44)161 306 4492
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Posted May 16, 2016.
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Acute induction of anomalous blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (LPS)
Etheresia Pretorius, Sthembile Mbotwa, Janette Bester, Christopher Robinson, Douglas B. Kell
bioRxiv 053538; doi: https://doi.org/10.1101/053538
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Acute induction of anomalous blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (LPS)
Etheresia Pretorius, Sthembile Mbotwa, Janette Bester, Christopher Robinson, Douglas B. Kell
bioRxiv 053538; doi: https://doi.org/10.1101/053538

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