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Genome-wide specificity profiles of CRISPR-Cas Cpf1 nucleases in human cells

Benjamin P. Kleinstiver, Shengdar Q. Tsai, Michelle S. Prew, Nhu T. Nguyen, Moira M. Welch, Jose M. Lopez, Zachary R. McCaw, Martin J. Aryee, J. Keiths Joung
doi: https://doi.org/10.1101/057802
Benjamin P. Kleinstiver
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
4Department of Pathology, Harvard Medical School, Boston, MA 02115 USA
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Shengdar Q. Tsai
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
4Department of Pathology, Harvard Medical School, Boston, MA 02115 USA
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Michelle S. Prew
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
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Nhu T. Nguyen
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
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Moira M. Welch
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
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Jose M. Lopez
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
4Department of Pathology, Harvard Medical School, Boston, MA 02115 USA
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Zachary R. McCaw
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
5Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA
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Martin J. Aryee
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
4Department of Pathology, Harvard Medical School, Boston, MA 02115 USA
5Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA
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J. Keiths Joung
1Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA 02129 USA
2Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 USA
3Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129 USA
4Department of Pathology, Harvard Medical School, Boston, MA 02115 USA
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Posted June 09, 2016.
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Genome-wide specificity profiles of CRISPR-Cas Cpf1 nucleases in human cells
Benjamin P. Kleinstiver, Shengdar Q. Tsai, Michelle S. Prew, Nhu T. Nguyen, Moira M. Welch, Jose M. Lopez, Zachary R. McCaw, Martin J. Aryee, J. Keiths Joung
bioRxiv 057802; doi: https://doi.org/10.1101/057802
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Genome-wide specificity profiles of CRISPR-Cas Cpf1 nucleases in human cells
Benjamin P. Kleinstiver, Shengdar Q. Tsai, Michelle S. Prew, Nhu T. Nguyen, Moira M. Welch, Jose M. Lopez, Zachary R. McCaw, Martin J. Aryee, J. Keiths Joung
bioRxiv 057802; doi: https://doi.org/10.1101/057802

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