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Estimate of disease heritability using 7.4 million familial relationships inferred from electronic health records

View ORCID ProfileFernanda Polubriaginof, Rami Vanguri, Kayla Quinnies, Gillian M. Belbin, Alexandre Yahi, Hojjat Salmasian, Tal Lorberbaum, Victor Nwankwo, Li Li, Mark Shervey, Patricia Glowe, Iuliana Ionita-Laza, Mary Simmerling, George Hripcsak, Suzanne Bakken, David Goldstein, Krzysztof Kiryluk, Eimear E. Kenny, Joel Dudley, David K. Vawdrey, View ORCID ProfileNicholas P. Tatonetti
doi: https://doi.org/10.1101/066068
Fernanda Polubriaginof
1Department of Biomedical Informatics, Columbia University, New York, NY
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Rami Vanguri
1Department of Biomedical Informatics, Columbia University, New York, NY
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Kayla Quinnies
1Department of Biomedical Informatics, Columbia University, New York, NY
2Institute for Genomic Medicine, Columbia University, New York, NY
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Gillian M. Belbin
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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Alexandre Yahi
1Department of Biomedical Informatics, Columbia University, New York, NY
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Hojjat Salmasian
1Department of Biomedical Informatics, Columbia University, New York, NY
4Value Institute, NewYork-Presbyterian Hospital, New York, NY
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Tal Lorberbaum
1Department of Biomedical Informatics, Columbia University, New York, NY
5Department of Physiology and Cellular Biophysics, Columbia University, New York, NY
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Victor Nwankwo
1Department of Biomedical Informatics, Columbia University, New York, NY
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Li Li
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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Mark Shervey
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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Patricia Glowe
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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Iuliana Ionita-Laza
6Mailman School of Public Health, Columbia University, New York, NY
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Mary Simmerling
7Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY
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George Hripcsak
1Department of Biomedical Informatics, Columbia University, New York, NY
8Medical Informatics Services, NewYork-Presbyterian Hospital, New York, NY
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Suzanne Bakken
1Department of Biomedical Informatics, Columbia University, New York, NY
9School of Nursing, Columbia University, New York, NY
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David Goldstein
2Institute for Genomic Medicine, Columbia University, New York, NY
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Krzysztof Kiryluk
10Department of Medicine, Columbia University, New York, NY
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Eimear E. Kenny
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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Joel Dudley
3Department of Genetics and Genomic Sciences, Mount Sinai Health System, New York, NY
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David K. Vawdrey
1Department of Biomedical Informatics, Columbia University, New York, NY
4Value Institute, NewYork-Presbyterian Hospital, New York, NY
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Nicholas P. Tatonetti
1Department of Biomedical Informatics, Columbia University, New York, NY
2Institute for Genomic Medicine, Columbia University, New York, NY
10Department of Medicine, Columbia University, New York, NY
11Department of Systems Biology, Columbia University, New York, NY
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  • ORCID record for Nicholas P. Tatonetti
  • For correspondence: nick.tatonetti@columbia.edu
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Estimate of disease heritability using 7.4 million familial relationships inferred from electronic health records
Fernanda Polubriaginof, Rami Vanguri, Kayla Quinnies, Gillian M. Belbin, Alexandre Yahi, Hojjat Salmasian, Tal Lorberbaum, Victor Nwankwo, Li Li, Mark Shervey, Patricia Glowe, Iuliana Ionita-Laza, Mary Simmerling, George Hripcsak, Suzanne Bakken, David Goldstein, Krzysztof Kiryluk, Eimear E. Kenny, Joel Dudley, David K. Vawdrey, Nicholas P. Tatonetti
bioRxiv 066068; doi: https://doi.org/10.1101/066068
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Estimate of disease heritability using 7.4 million familial relationships inferred from electronic health records
Fernanda Polubriaginof, Rami Vanguri, Kayla Quinnies, Gillian M. Belbin, Alexandre Yahi, Hojjat Salmasian, Tal Lorberbaum, Victor Nwankwo, Li Li, Mark Shervey, Patricia Glowe, Iuliana Ionita-Laza, Mary Simmerling, George Hripcsak, Suzanne Bakken, David Goldstein, Krzysztof Kiryluk, Eimear E. Kenny, Joel Dudley, David K. Vawdrey, Nicholas P. Tatonetti
bioRxiv 066068; doi: https://doi.org/10.1101/066068

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