Abstract
Genome-wide, cell-type-specific profiles are being systematically generated for numerous genomic and epigenomic features. There is, however, no universally applicable analytical methodology for such data. We present GSuite HyperBrowser, the first comprehensive solution for integrative analysis of dataset collections across the genome and epigenome. The GSuite HyperBrowser is an open-source system for streamlined acquisition and customizable statistical analysis of large collections of genome-wide datasets. The system is based on new computational and statistical methodologies that permit comparative and confirmatory analyses across multiple disparate data sources. Expert guidance and reproducibility are facilitated via a Galaxy-based web-interface. The software is available at https://hyperbrowser.uio.no/gsuite
List of abbreviations
- ENCODE
- The Encyclopedia of DNA Elements;
- SNP
- Single Nucleotide Polymorphism;
- TF
- Transcription Factor;
- URI
- Uniform Resource Identifier;
- URL
- Uniform Resource Locator
