Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

Michael G. Napolitano; Matthieu Landon; Christopher J. Gregg; Marc J. Lajoie; Lakshmi N. Govindarajan; Joshua A. Mosberg; Gleb Kuznetsov; Daniel B. Goodman; Oscar Vargas-Rodriguez; Farren J. Isaacs; Dieter Söll; George M. Church

doi:10.1101/069385

New Results

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

View ORCID ProfileMichael G. Napolitano, Matthieu Landon, Christopher J. Gregg, Marc J. Lajoie, Lakshmi N. Govindarajan, Joshua A. Mosberg, Gleb Kuznetsov, Daniel B. Goodman, Oscar Vargas-Rodriguez, Farren J. Isaacs, Dieter Söll, George M. Church

doi: https://doi.org/10.1101/069385

Michael G. Napolitano

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

‡Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Michael G. Napolitano

Matthieu Landon

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

2Systems Biology Graduate Program, Harvard Medical School, Boston, MA 02115

5Ecole des Mines de Paris, Mines Paristech, 75272 Paris, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christopher J. Gregg

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Marc J. Lajoie

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

†Program in Chemical Biology, Harvard University, Cambridge, MA 02138

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Lakshmi N. Govindarajan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Joshua A. Mosberg

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

†Program in Chemical Biology, Harvard University, Cambridge, MA 02138

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Gleb Kuznetsov

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

4Program in Biophysics, Harvard University, Boston, Massachusetts 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Daniel B. Goodman

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

6Harvard-MIT Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Oscar Vargas-Rodriguez

7Department of Molecular Biophysics and Biochemistry Yale University, New Haven, CT 06516, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Farren J. Isaacs

3Molecular, Cellular, Developmental & Systems Biology Institute, Yale University, New Haven, CT 06516, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Dieter Söll

7Department of Molecular Biophysics and Biochemistry Yale University, New Haven, CT 06516, USA

8Department of Chemistry Yale University, New Haven, CT 06516, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

George M. Church

1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

Supplemental Table 1
Supplemental Table 2
Supplemental Table 3
Supplemental Table 4
Supplemental Table 5
Supplemental Table 6
Supplemental Table 7
Supplemental Table 8

View the discussion thread.

PreviousNext

Posted August 14, 2016.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

Michael G. Napolitano, Matthieu Landon, Christopher J. Gregg, Marc J. Lajoie, Lakshmi N. Govindarajan, Joshua A. Mosberg, Gleb Kuznetsov, Daniel B. Goodman, Oscar Vargas-Rodriguez, Farren J. Isaacs, Dieter Söll, George M. Church

bioRxiv 069385; doi: https://doi.org/10.1101/069385

Share This Article: