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Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
View ORCID ProfileMichael G. Napolitano, Matthieu Landon, Christopher J. Gregg, Marc J. Lajoie, Lakshmi N. Govindarajan, Joshua A. Mosberg, Gleb Kuznetsov, Daniel B. Goodman, Oscar Vargas-Rodriguez, Farren J. Isaacs, Dieter Söll, George M. Church
doi: https://doi.org/10.1101/069385
Michael G. Napolitano
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
‡Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115
Matthieu Landon
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
2Systems Biology Graduate Program, Harvard Medical School, Boston, MA 02115
5Ecole des Mines de Paris, Mines Paristech, 75272 Paris, France
Christopher J. Gregg
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
Marc J. Lajoie
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
†Program in Chemical Biology, Harvard University, Cambridge, MA 02138
Lakshmi N. Govindarajan
Joshua A. Mosberg
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
†Program in Chemical Biology, Harvard University, Cambridge, MA 02138
Gleb Kuznetsov
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
4Program in Biophysics, Harvard University, Boston, Massachusetts 02115, USA
Daniel B. Goodman
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
6Harvard-MIT Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
Oscar Vargas-Rodriguez
7Department of Molecular Biophysics and Biochemistry Yale University, New Haven, CT 06516, USA
Farren J. Isaacs
3Molecular, Cellular, Developmental & Systems Biology Institute, Yale University, New Haven, CT 06516, USA
Dieter Söll
7Department of Molecular Biophysics and Biochemistry Yale University, New Haven, CT 06516, USA
8Department of Chemistry Yale University, New Haven, CT 06516, USA
George M. Church
1Department of Genetics & Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, MA 02115
Posted August 14, 2016.
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
Michael G. Napolitano, Matthieu Landon, Christopher J. Gregg, Marc J. Lajoie, Lakshmi N. Govindarajan, Joshua A. Mosberg, Gleb Kuznetsov, Daniel B. Goodman, Oscar Vargas-Rodriguez, Farren J. Isaacs, Dieter Söll, George M. Church
bioRxiv 069385; doi: https://doi.org/10.1101/069385
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
Michael G. Napolitano, Matthieu Landon, Christopher J. Gregg, Marc J. Lajoie, Lakshmi N. Govindarajan, Joshua A. Mosberg, Gleb Kuznetsov, Daniel B. Goodman, Oscar Vargas-Rodriguez, Farren J. Isaacs, Dieter Söll, George M. Church
bioRxiv 069385; doi: https://doi.org/10.1101/069385
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