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Ordinary Differential Equations in Cancer Biology

Margaret P. Chapman, Claire J. Tomlin
doi: https://doi.org/10.1101/071134
Margaret P. Chapman
Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, 94720 USA (email: ).
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  • For correspondence: chapmanm@berkeley.edu
Claire J. Tomlin
Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, 94720 USA (email: ).
Roles: ICBP Member
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  • For correspondence: chapmanm@berkeley.edu
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Abstract

Ordinary differential equations (ODEs) provide a classical framework to model the dynamics of biological systems, given temporal experimental data. Qualitative analysis of the ODE model can lead to further biological insight and deeper understanding compared to traditional experiments alone. Simulation of the model under various perturbations can generate novel hypotheses and motivate the design of new experiments. This short paper will provide an overview of the ODE modeling framework, and present examples of how ODEs can be used to address problems in cancer biology.

Footnotes

  • Chapman is supported by a Berkeley Graduate Fellowship.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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Posted August 23, 2016.
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Ordinary Differential Equations in Cancer Biology
Margaret P. Chapman, Claire J. Tomlin
bioRxiv 071134; doi: https://doi.org/10.1101/071134
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Ordinary Differential Equations in Cancer Biology
Margaret P. Chapman, Claire J. Tomlin
bioRxiv 071134; doi: https://doi.org/10.1101/071134

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