Hepatocyte nuclear factor 4-mediated lipotoxicity provokes mitochondrial damage in peroxisome-deficient pex19 mutants

Margret H. Bülow; Julia Sellin; Christian Wingen; Deniz Senyilmaz; Dominic Gosejacob; Aurelio A. Teleman; Michael Hoch

doi:10.1101/071787

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Hepatocyte nuclear factor 4-mediated lipotoxicity provokes mitochondrial damage in peroxisome-deficient pex19 mutants

Margret H. Bülow, Julia Sellin, Christian Wingen, Deniz Senyilmaz, Dominic Gosejacob, Aurelio A. Teleman, Michael Hoch

doi: https://doi.org/10.1101/071787

Margret H. Bülow

1University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Carl-Troll-Straße 31, 53115 Bonn, Germany

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Julia Sellin

1University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Carl-Troll-Straße 31, 53115 Bonn, Germany

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Christian Wingen

1University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Carl-Troll-Straße 31, 53115 Bonn, Germany

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Deniz Senyilmaz

2German Cancer Research Center, Signal Transduction in Cancer and Metabolism, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany

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Dominic Gosejacob

1University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Carl-Troll-Straße 31, 53115 Bonn, Germany

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Aurelio A. Teleman

2German Cancer Research Center, Signal Transduction in Cancer and Metabolism, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany

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Michael Hoch

1University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Carl-Troll-Straße 31, 53115 Bonn, Germany

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For correspondence: m.hoch@uni-bonn.de

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Posted August 26, 2016.

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Hepatocyte nuclear factor 4-mediated lipotoxicity provokes mitochondrial damage in peroxisome-deficient pex19 mutants

Margret H. Bülow, Julia Sellin, Christian Wingen, Deniz Senyilmaz, Dominic Gosejacob, Aurelio A. Teleman, Michael Hoch

bioRxiv 071787; doi: https://doi.org/10.1101/071787

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Hepatocyte nuclear factor 4-mediated lipotoxicity provokes mitochondrial damage in peroxisome-deficient pex19 mutants

Margret H. Bülow, Julia Sellin, Christian Wingen, Deniz Senyilmaz, Dominic Gosejacob, Aurelio A. Teleman, Michael Hoch

bioRxiv 071787; doi: https://doi.org/10.1101/071787

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