Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Zika virus replication in the mosquito Culex quinquefasciatus in Brazil

D. R. D. Guedes, M. H. S. Paiva, M. M. A. Donato, P. P. Barbosa, L. Krokovsky, S. W. dos S. Rocha, K. L. A. Saraiva, M. M. Crespo, R. M. R. Barbosa, C. M. F. Oliveira, M. A. V. Melo-Santos, L. Pena, M. T. Cordeiro, R. F. de O. França, A. L. S, de Oliveira, W. S. Leal, C. A. Peixoto, C. F. J. Ayres
doi: https://doi.org/10.1101/073197
D. R. D. Guedes
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. H. S. Paiva
2Universidade Federal de Pernambuco, Centro Acadêmico do Agreste - Rodovia BR-104, km 59 - Nova Caruaru, Caruaru - PE – Brazil, CEP: 55002-970.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. M. A. Donato
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. P. Barbosa
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Krokovsky
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. W. dos S. Rocha
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K. L. A. Saraiva
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. M. Crespo
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. M. R. Barbosa
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. M. F. Oliveira
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. A. V. Melo-Santos
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Pena
3Laboratory of Virology and Experimental Therapy (LAVITE), Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. T. Cordeiro
3Laboratory of Virology and Experimental Therapy (LAVITE), Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. F. de O. França
3Laboratory of Virology and Experimental Therapy (LAVITE), Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. L. S, de Oliveira
4Center for Statistics and Geoprocessing, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W. S. Leal
5Department of Molecular and Cellular Biology, University of California-Davis, Davis, CA, 95616 USA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. A. Peixoto
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. F. J. Ayres
1Department of Entomology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz-Pernambuco. Av. Moraes Rego, s/n campus da UFPE, Cidade Universitária, Recife-PE, Brazil, CEP: 50670-420.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: tans@cpqam.fiocruz.br
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Zika virus (ZIKV) is a flavivirus that has recently been associated with increased incidence of neonatal microcephaly and other neurological disorders. The virus is primarily transmitted by mosquito bite, although other routes of infection have been implicated in some cases. The Aedes aegypti mosquito is considered to be the main vector to humans worldwide, but there is evidence of other mosquito species, including Culex quinquefasciatus, playing a role in the Brazilian outbreak. To test this hypothesis, we experimentally compared the vectorial competence of laboratory-reared A. aegypti and C. quinquefasciatus. We found ZIKV in the midgut, salivary glands, and saliva of artificially fed C. quinquefasciatus. Additionally, we collected ZIKV-infected C. quinquefasciatus from urban areas of high microcephaly incidence in Recife, Brazil. Take into account; these findings indicate that there may be a wider range of vectors for ZIKV than anticipated.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted September 02, 2016.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Zika virus replication in the mosquito Culex quinquefasciatus in Brazil
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Zika virus replication in the mosquito Culex quinquefasciatus in Brazil
D. R. D. Guedes, M. H. S. Paiva, M. M. A. Donato, P. P. Barbosa, L. Krokovsky, S. W. dos S. Rocha, K. L. A. Saraiva, M. M. Crespo, R. M. R. Barbosa, C. M. F. Oliveira, M. A. V. Melo-Santos, L. Pena, M. T. Cordeiro, R. F. de O. França, A. L. S, de Oliveira, W. S. Leal, C. A. Peixoto, C. F. J. Ayres
bioRxiv 073197; doi: https://doi.org/10.1101/073197
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Zika virus replication in the mosquito Culex quinquefasciatus in Brazil
D. R. D. Guedes, M. H. S. Paiva, M. M. A. Donato, P. P. Barbosa, L. Krokovsky, S. W. dos S. Rocha, K. L. A. Saraiva, M. M. Crespo, R. M. R. Barbosa, C. M. F. Oliveira, M. A. V. Melo-Santos, L. Pena, M. T. Cordeiro, R. F. de O. França, A. L. S, de Oliveira, W. S. Leal, C. A. Peixoto, C. F. J. Ayres
bioRxiv 073197; doi: https://doi.org/10.1101/073197

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Microbiology
Subject Areas
All Articles
  • Animal Behavior and Cognition (3704)
  • Biochemistry (7834)
  • Bioengineering (5708)
  • Bioinformatics (21366)
  • Biophysics (10614)
  • Cancer Biology (8218)
  • Cell Biology (11989)
  • Clinical Trials (138)
  • Developmental Biology (6793)
  • Ecology (10433)
  • Epidemiology (2065)
  • Evolutionary Biology (13920)
  • Genetics (9736)
  • Genomics (13118)
  • Immunology (8182)
  • Microbiology (20092)
  • Molecular Biology (7886)
  • Neuroscience (43206)
  • Paleontology (321)
  • Pathology (1285)
  • Pharmacology and Toxicology (2270)
  • Physiology (3367)
  • Plant Biology (7263)
  • Scientific Communication and Education (1317)
  • Synthetic Biology (2012)
  • Systems Biology (5552)
  • Zoology (1135)