Abstract
Summary GenomeScope is an open-source web tool to rapidly estimate the overall characteristics of a genome, including genome size, heterozygosity rate, and repeat content from unprocessed short reads. These features are essential for studying genome evolution, and help to choose parameters for downstream analysis. We demonstrate its accuracy on 324 simulated and 16 real datasets with a wide range in genome sizes, heterozygosity levels, and error rates.
Availability and Implementation http://qb.cshl.edu/genomescope/, https://github.com/schatzlab/genomescope.git
Contact mschatz@jhu.edu
Supplementary information Supplementary data are available at Bioinformatics online.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Posted September 19, 2016.
