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The rate of false polymorphisms introduced when imputing genotypes from global imputation panels

Ida Surakka, Antti-Pekka Sarin, Sanni E Ruotsalainen, Richard Durbin, Veikko Salomaa, Mark J Daly, Aarno Palotie, Samuli Ripatti, SISu project group
doi: https://doi.org/10.1101/080770
Ida Surakka
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
2Department of Health, National Institute for Health and Welfare, Helsinki, Finland
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Antti-Pekka Sarin
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
2Department of Health, National Institute for Health and Welfare, Helsinki, Finland
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Sanni E Ruotsalainen
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
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Richard Durbin
3Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
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Veikko Salomaa
2Department of Health, National Institute for Health and Welfare, Helsinki, Finland
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Mark J Daly
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
4Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
5Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
6Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
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Aarno Palotie
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
4Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
6Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
7Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
8Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
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Samuli Ripatti
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
3Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
9Department of Public Health, University of Helsinki, Helsinki, Finland
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Article Information

doi 
https://doi.org/10.1101/080770
History 
  • October 13, 2016.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Ida Surakka1,2,
  2. Antti-Pekka Sarin1,2,
  3. Sanni E Ruotsalainen1,
  4. Richard Durbin3,
  5. Veikko Salomaa2,
  6. Mark J Daly1,4,5,6,
  7. Aarno Palotie1,4,6,7,8,
  8. Samuli Ripatti1,3,9,*,
  9. SISu project group
  1. 1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
  2. 2Department of Health, National Institute for Health and Welfare, Helsinki, Finland
  3. 3Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
  4. 4Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
  5. 5Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
  6. 6Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
  7. 7Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
  8. 8Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
  9. 9Department of Public Health, University of Helsinki, Helsinki, Finland
  1. ↵*Corresponding author
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Posted October 13, 2016.
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The rate of false polymorphisms introduced when imputing genotypes from global imputation panels
Ida Surakka, Antti-Pekka Sarin, Sanni E Ruotsalainen, Richard Durbin, Veikko Salomaa, Mark J Daly, Aarno Palotie, Samuli Ripatti, SISu project group
bioRxiv 080770; doi: https://doi.org/10.1101/080770
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The rate of false polymorphisms introduced when imputing genotypes from global imputation panels
Ida Surakka, Antti-Pekka Sarin, Sanni E Ruotsalainen, Richard Durbin, Veikko Salomaa, Mark J Daly, Aarno Palotie, Samuli Ripatti, SISu project group
bioRxiv 080770; doi: https://doi.org/10.1101/080770

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