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Metabolomic and proteomic analyses of a quiescent Escherichia coli cell factory reveal the mechanisms behind its production efficiency

View ORCID ProfileNicholas M. Thomson, Tomokazu Shirai, Marco Chiapello, Akihiko Kondo, Krishnan J. Mukherjee, Easan Sivaniah, David K. Summers, Keiji Numata
doi: https://doi.org/10.1101/082305
Nicholas M. Thomson
1Enzyme Research Team, RIKEN Biomass Engineering Program, 2-1 Hirosawa, Wako-shi, Saitama, 351-0198, Japan
6Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK
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  • ORCID record for Nicholas M. Thomson
  • For correspondence: nthomson@cantab.net keiji.numata@riken.jp
Tomokazu Shirai
2Cell Factory Research Team, RIKEN Biomass Engineering Program, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan
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Marco Chiapello
3Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK
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Akihiko Kondo
2Cell Factory Research Team, RIKEN Biomass Engineering Program, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan
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Krishnan J. Mukherjee
4School of Biotechnology, Jawaharlal Nehru University, New Delhi-110067, India
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Easan Sivaniah
5Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8501, Japan
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David K. Summers
6Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK
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Keiji Numata
1Enzyme Research Team, RIKEN Biomass Engineering Program, 2-1 Hirosawa, Wako-shi, Saitama, 351-0198, Japan
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  • For correspondence: nthomson@cantab.net keiji.numata@riken.jp
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Article Information

doi 
https://doi.org/10.1101/082305
History 
  • October 20, 2016.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Nicholas M. Thomson1,6,*,
  2. Tomokazu Shirai2,
  3. Marco Chiapello3,
  4. Akihiko Kondo2,
  5. Krishnan J. Mukherjee4,
  6. Easan Sivaniah5,
  7. David K. Summers6 and
  8. Keiji Numata1,*
  1. 1Enzyme Research Team, RIKEN Biomass Engineering Program, 2-1 Hirosawa, Wako-shi, Saitama, 351-0198, Japan
  2. 2Cell Factory Research Team, RIKEN Biomass Engineering Program, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan
  3. 3Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK
  4. 4School of Biotechnology, Jawaharlal Nehru University, New Delhi-110067, India
  5. 5Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8501, Japan
  6. 6Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK
  1. ↵*Corresponding authors. Email: nthomson{at}cantab.net Phone: +44(0)1223333985 Email: keiji.numata{at}riken.jp Phone: +81(0)484679525
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Posted October 20, 2016.
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Metabolomic and proteomic analyses of a quiescent Escherichia coli cell factory reveal the mechanisms behind its production efficiency
Nicholas M. Thomson, Tomokazu Shirai, Marco Chiapello, Akihiko Kondo, Krishnan J. Mukherjee, Easan Sivaniah, David K. Summers, Keiji Numata
bioRxiv 082305; doi: https://doi.org/10.1101/082305
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Metabolomic and proteomic analyses of a quiescent Escherichia coli cell factory reveal the mechanisms behind its production efficiency
Nicholas M. Thomson, Tomokazu Shirai, Marco Chiapello, Akihiko Kondo, Krishnan J. Mukherjee, Easan Sivaniah, David K. Summers, Keiji Numata
bioRxiv 082305; doi: https://doi.org/10.1101/082305

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