Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer

Richard C. Sallari, Nicholas A. Sinnott-Armstrong, Juliet D. French, Ken J. Kron, Jason Ho, Jason H. Moore, Vuk Stambolic, Stacey L. Edwards, Mathieu Lupien, Manolis Kellis
doi: https://doi.org/10.1101/097451
Richard C. Sallari
1Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA
2The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: sallari@mit.edu manoli@mit.edu
Nicholas A. Sinnott-Armstrong
3Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Juliet D. French
4Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ken J. Kron
5The Princess Margaret Cancer Centre — University Health Network, Toronto, Ontario M5G 1L7, Canada
6Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jason Ho
5The Princess Margaret Cancer Centre — University Health Network, Toronto, Ontario M5G 1L7, Canada
6Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jason H. Moore
7Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vuk Stambolic
5The Princess Margaret Cancer Centre — University Health Network, Toronto, Ontario M5G 1L7, Canada
6Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stacey L. Edwards
4Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mathieu Lupien
5The Princess Margaret Cancer Centre — University Health Network, Toronto, Ontario M5G 1L7, Canada
6Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
8Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Manolis Kellis
1Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA
2The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: sallari@mit.edu manoli@mit.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Article Information

doi 
https://doi.org/10.1101/097451
History 
  • August 26, 2017.

Article Versions

  • Version 1 (December 30, 2016 - 15:21).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Richard C. Sallari1,2,*,
  2. Nicholas A. Sinnott-Armstrong3,
  3. Juliet D. French4,
  4. Ken J. Kron5,6,
  5. Jason Ho5,6,
  6. Jason H. Moore7,
  7. Vuk Stambolic5,6,
  8. Stacey L. Edwards4,
  9. Mathieu Lupien5,6,8 and
  10. Manolis Kellis1,2,*
  1. 1Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA
  2. 2The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
  3. 3Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
  4. 4Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia
  5. 5The Princess Margaret Cancer Centre — University Health Network, Toronto, Ontario M5G 1L7, Canada
  6. 6Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
  7. 7Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
  8. 8Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada
  1. ↵*Correspondence: sallari{at}mit.edu (R.C.S.), manoli{at}mit.edu (M.K.)
Back to top
PreviousNext
Posted August 26, 2017.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer
Richard C. Sallari, Nicholas A. Sinnott-Armstrong, Juliet D. French, Ken J. Kron, Jason Ho, Jason H. Moore, Vuk Stambolic, Stacey L. Edwards, Mathieu Lupien, Manolis Kellis
bioRxiv 097451; doi: https://doi.org/10.1101/097451
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer
Richard C. Sallari, Nicholas A. Sinnott-Armstrong, Juliet D. French, Ken J. Kron, Jason Ho, Jason H. Moore, Vuk Stambolic, Stacey L. Edwards, Mathieu Lupien, Manolis Kellis
bioRxiv 097451; doi: https://doi.org/10.1101/097451

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (4682)
  • Biochemistry (10357)
  • Bioengineering (7670)
  • Bioinformatics (26330)
  • Biophysics (13523)
  • Cancer Biology (10683)
  • Cell Biology (15438)
  • Clinical Trials (138)
  • Developmental Biology (8497)
  • Ecology (12820)
  • Epidemiology (2067)
  • Evolutionary Biology (16851)
  • Genetics (11399)
  • Genomics (15478)
  • Immunology (10616)
  • Microbiology (25207)
  • Molecular Biology (10220)
  • Neuroscience (54463)
  • Paleontology (401)
  • Pathology (1668)
  • Pharmacology and Toxicology (2897)
  • Physiology (4342)
  • Plant Biology (9243)
  • Scientific Communication and Education (1586)
  • Synthetic Biology (2557)
  • Systems Biology (6780)
  • Zoology (1466)