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Theoretical principles of multiscale spatiotemporal control of neuronal networks: a complex systems perspective

View ORCID ProfileNima Dehghani
doi: https://doi.org/10.1101/097618
Nima Dehghani
1New England Complex Systems Institute, Cambridge, MA
2Massachusetts Institute of Technology, Department of Physics, Cambridge, MA
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Abstract

Success in the fine control of the nervous system depends on a deeper understanding of how neural circuits control behavior. There is, however, a wide gap between the components of neural circuits and behavior. We advance the idea that a suitable approach for narrowing this gap has to be based on a multiscale information-theoretic description of the system. We evaluate the possibility that brain-wide complex neural computations can be dissected into a hierarchy of computational motifs that rely on smaller circuit modules interacting at multiple scales. In doing so, we draw attention to the importance of formalizing the goals of stimulation in terms of neural computations so that the possible implementations are matched in scale to the underlying circuit modules.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted January 01, 2017.
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Theoretical principles of multiscale spatiotemporal control of neuronal networks: a complex systems perspective
Nima Dehghani
bioRxiv 097618; doi: https://doi.org/10.1101/097618
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Theoretical principles of multiscale spatiotemporal control of neuronal networks: a complex systems perspective
Nima Dehghani
bioRxiv 097618; doi: https://doi.org/10.1101/097618

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