Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma

E. Mammadova-Bach; T. Rupp; C. Spenlé; I. Jivkov; P. Shankaranarayanan; A. Klein; L. Pisarsky; A. Méchine-Neuville; G. Cremel; M. Kedinger; O. De Wever; N. Ambartsumian; S. Robine; E. Pencreach; D. Guenot; J.G. Goetz; P. Simon-Assmann; G. Orend; O. Lefebvre

doi:10.1101/099465

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Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma

E. Mammadova-Bach, T. Rupp, C. Spenlé, I. Jivkov, P. Shankaranarayanan, A. Klein, L. Pisarsky, A. Méchine-Neuville, G. Cremel, M. Kedinger, O. De Wever, N. Ambartsumian, S. Robine, E. Pencreach, D. Guenot, View ORCID ProfileJ.G. Goetz, P. Simon-Assmann, G. Orend, O. Lefebvre

doi: https://doi.org/10.1101/099465

E. Mammadova-Bach

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

5present address, Inserm UMR-S 949, Etablissement Français du Sang-Alsace, Strasbourg, F-67065, France.

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T. Rupp

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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C. Spenlé

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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I. Jivkov

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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P. Shankaranarayanan

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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A. Klein

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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L. Pisarsky

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

6present Adress, Public Health Sciences Division/Translational Research Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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A. Méchine-Neuville

7Department of Anatomy and Pathology, CHRU Hautepierre, Strasbourg, F-67200, France.

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G. Cremel

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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M. Kedinger

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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O. De Wever

8laboratory of Experimental Cancer Research, Department of Radiotherapy and Nuclear Medicine, Ghent University Hospital, Ghent, 9000, Belgium.

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N. Ambartsumian

9Institut for Cancer Biology, Copenhagen, DK-2100, Denmark.

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S. Robine

10Institut Curie, Paris, F-75248, France.

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E. Pencreach

11EA 3430, Université de Strasbourg, Strasbourg, F-67000, France.

12Plateforme de Génétique Moléculaire des Cancers, Hôpitaux Universitaires de Strasbourg, Strasbourg, F-67098, France.

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D. Guenot

11EA 3430, Université de Strasbourg, Strasbourg, F-67000, France.

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J.G. Goetz

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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ORCID record for J.G. Goetz
For correspondence: jacky.goetz@inserm.fr gertraud.orend@inserm.fr olivier.lefebvre@inserm.fr

P. Simon-Assmann

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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G. Orend

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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For correspondence: jacky.goetz@inserm.fr gertraud.orend@inserm.fr olivier.lefebvre@inserm.fr

O. Lefebvre

1Inserm U1109, MN3T, Strasbourg, F-67200, France.

2Université de Strasbourg, Strasbourg, F-67000, France.

3LabEx Medalis, Université de Strasbourg, Strasbourg, F-67000, France.

4Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, F-67000, France.

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For correspondence: jacky.goetz@inserm.fr gertraud.orend@inserm.fr olivier.lefebvre@inserm.fr

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Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma

E. Mammadova-Bach, T. Rupp, C. Spenlé, I. Jivkov, P. Shankaranarayanan, A. Klein, L. Pisarsky, A. Méchine-Neuville, G. Cremel, M. Kedinger, O. De Wever, N. Ambartsumian, S. Robine, E. Pencreach, D. Guenot, J.G. Goetz, P. Simon-Assmann, G. Orend, O. Lefebvre

bioRxiv 099465; doi: https://doi.org/10.1101/099465

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Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma

E. Mammadova-Bach, T. Rupp, C. Spenlé, I. Jivkov, P. Shankaranarayanan, A. Klein, L. Pisarsky, A. Méchine-Neuville, G. Cremel, M. Kedinger, O. De Wever, N. Ambartsumian, S. Robine, E. Pencreach, D. Guenot, J.G. Goetz, P. Simon-Assmann, G. Orend, O. Lefebvre

bioRxiv 099465; doi: https://doi.org/10.1101/099465

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