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Stem cell differentiation is a stochastic process with memory

View ORCID ProfilePatrick S. Stumpf, View ORCID ProfileRosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann Babtie, Thalia E. Chan, Michael P. H. Stumpf, Colin P. Please, Sam D. Howison, Fumio Arai, Ben D. MacArthur
doi: https://doi.org/10.1101/101048
Patrick S. Stumpf
1Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, SO17 1BJ, United Kingdom
2Institute for Life Sciences, University of Southampton, SO17 1BJ, United Kingdom
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  • ORCID record for Patrick S. Stumpf
Rosanna C. G. Smith
1Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, SO17 1BJ, United Kingdom
2Institute for Life Sciences, University of Southampton, SO17 1BJ, United Kingdom
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  • ORCID record for Rosanna C. G. Smith
Michael Lenz
3Joint Research Center for Computational Biomedicine, RWTH Aachen University, 52056, Aachen, Germany
4Aachen Institute for Advanced Study in Computational Engineering Science, RWTH Aachen University, 52062, Aachen, Germany
5Maastricht Centre for Systems Biology, Maastricht University, 6229 ER, Maastricht, Netherlands
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Andreas Schuppert
3Joint Research Center for Computational Biomedicine, RWTH Aachen University, 52056, Aachen, Germany
4Aachen Institute for Advanced Study in Computational Engineering Science, RWTH Aachen University, 52062, Aachen, Germany
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Franz-Josef Müller
6Zentrum für Integrative Psychiatrie, 24105, Kiel, Germany
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Ann Babtie
7Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom
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Thalia E. Chan
7Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom
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Michael P. H. Stumpf
7Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom
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Colin P. Please
8Mathematical Institute, University of Oxford, Oxford, OX2 6GG, United Kingdom
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Sam D. Howison
8Mathematical Institute, University of Oxford, Oxford, OX2 6GG, United Kingdom
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Fumio Arai
9Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan
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Ben D. MacArthur
1Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, SO17 1BJ, United Kingdom
2Institute for Life Sciences, University of Southampton, SO17 1BJ, United Kingdom
10Mathematical Sciences, University of Southampton, SO17 1BJ, United Kingdom
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  • For correspondence: bdm@soton.ac.uk
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Stem cell differentiation is a stochastic process with memory
Patrick S. Stumpf, Rosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann Babtie, Thalia E. Chan, Michael P. H. Stumpf, Colin P. Please, Sam D. Howison, Fumio Arai, Ben D. MacArthur
bioRxiv 101048; doi: https://doi.org/10.1101/101048
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Stem cell differentiation is a stochastic process with memory
Patrick S. Stumpf, Rosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann Babtie, Thalia E. Chan, Michael P. H. Stumpf, Colin P. Please, Sam D. Howison, Fumio Arai, Ben D. MacArthur
bioRxiv 101048; doi: https://doi.org/10.1101/101048

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