Stem cell differentiation is a stochastic process with memory

Patrick S. Stumpf; Rosanna C. G. Smith; Michael Lenz; Andreas Schuppert; Franz-Josef Müller; Ann Babtie; Thalia E. Chan; Michael P. H. Stumpf; Colin P. Please; Sam D. Howison; Fumio Arai; Ben D. MacArthur

doi:10.1101/101048

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Stem cell differentiation is a stochastic process with memory

View ORCID ProfilePatrick S. Stumpf, View ORCID ProfileRosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann Babtie, Thalia E. Chan, Michael P. H. Stumpf, Colin P. Please, Sam D. Howison, Fumio Arai, Ben D. MacArthur

doi: https://doi.org/10.1101/101048

Patrick S. Stumpf

Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, SO17 1BJ, United KingdomInstitute for Life Sciences, University of Southampton, SO17 1BJ, United Kingdom

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ORCID record for Patrick S. Stumpf

Rosanna C. G. Smith

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ORCID record for Rosanna C. G. Smith

Michael Lenz

Joint Research Center for Computational Biomedicine, RWTH Aachen University, 52056, Aachen, GermanyAachen Institute for Advanced Study in Computational Engineering Science, RWTH Aachen University, 52062, Aachen, GermanyMaastricht Centre for Systems Biology, Maastricht University, 6229 ER, Maastricht, Netherlands

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Andreas Schuppert

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Franz-Josef Müller

Zentrum für Integrative Psychiatrie, 24105, Kiel, Germany

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Ann Babtie

Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom

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Thalia E. Chan

Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom

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Michael P. H. Stumpf

Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College, London SW7 2AZ, United Kingdom

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Colin P. Please

Mathematical Institute, University of Oxford, Oxford, OX2 6GG, United Kingdom

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Sam D. Howison

Mathematical Institute, University of Oxford, Oxford, OX2 6GG, United Kingdom

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Fumio Arai

Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan

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Ben D. MacArthur

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For correspondence: bdm@soton.ac.uk

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Posted January 17, 2017.

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Stem cell differentiation is a stochastic process with memory

Patrick S. Stumpf, Rosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann Babtie, Thalia E. Chan, Michael P. H. Stumpf, Colin P. Please, Sam D. Howison, Fumio Arai, Ben D. MacArthur

bioRxiv 101048; doi: https://doi.org/10.1101/101048

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