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A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial

Matthew Matlock, Na Le Dang, David Brown, View ORCID ProfileS. Joshua Swamidass
doi: https://doi.org/10.1101/102111
Matthew Matlock
1Washington University School of Medicine. Saint Louis, MO 63110
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Na Le Dang
1Washington University School of Medicine. Saint Louis, MO 63110
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David Brown
1Washington University School of Medicine. Saint Louis, MO 63110
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S. Joshua Swamidass
1Washington University School of Medicine. Saint Louis, MO 63110
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  • ORCID record for S. Joshua Swamidass
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Abstract

The racial composition of treatment centers in the SPRINT trial is an independent risk factor for myocardial infarction (MI) and stroke. Independent of individual race or ethnicity, patients face a 39% increase in relative risk of MI or stroke when associated to treatment centers with a high proportion of African Americans. The magnitude of this effect is comparable to smoking. This suggests the strong influence of social determinants on health outcomes among hypertensive patients.

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Posted March 05, 2017.
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A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial
Matthew Matlock, Na Le Dang, David Brown, S. Joshua Swamidass
bioRxiv 102111; doi: https://doi.org/10.1101/102111
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A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial
Matthew Matlock, Na Le Dang, David Brown, S. Joshua Swamidass
bioRxiv 102111; doi: https://doi.org/10.1101/102111

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