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Constraining CD45 exclusion at close-contacts provides a mechanism for discriminatory T-cell receptor signalling
View ORCID ProfileRicardo A Fernandes, Kristina A Ganzinger, Justin Tzou, Peter Jönsson, Steven F Lee, Matthieu Palayret, Ana Mafalda Santos, Veronica T Chang, Charlotte Macleod, B. Christoffer Lagerholm, Alan E. Lindsay, Omer Dushek, Andreas Tilevik, Simon J Davis, David Klenerman
doi: https://doi.org/10.1101/109785
Ricardo A Fernandes
1Radcliffe Department of Medicine and MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom
Kristina A Ganzinger
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
Justin Tzou
5Mathematics Department, University of British Columbia, Vancouver, BC, V6T 1Z2, Canada.
Peter Jönsson
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
Steven F Lee
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
Matthieu Palayret
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
Ana Mafalda Santos
1Radcliffe Department of Medicine and MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom
Veronica T Chang
1Radcliffe Department of Medicine and MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom
Charlotte Macleod
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
B. Christoffer Lagerholm
1Radcliffe Department of Medicine and MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom
Alan E. Lindsay
4Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, USA, 46556.
Omer Dushek
3Sir William Dunn School of Pathology, University of Oxford, Oxford, UK; Wolfson Centre for Mathematical Biology, University of Oxford, Oxford, UK.
Andreas Tilevik
6School of Bioscience, University of Skövde, 541 28 Skövde, Sweden
Simon J Davis
1Radcliffe Department of Medicine and MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom
David Klenerman
2Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom
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Posted February 19, 2017.
Constraining CD45 exclusion at close-contacts provides a mechanism for discriminatory T-cell receptor signalling
Ricardo A Fernandes, Kristina A Ganzinger, Justin Tzou, Peter Jönsson, Steven F Lee, Matthieu Palayret, Ana Mafalda Santos, Veronica T Chang, Charlotte Macleod, B. Christoffer Lagerholm, Alan E. Lindsay, Omer Dushek, Andreas Tilevik, Simon J Davis, David Klenerman
bioRxiv 109785; doi: https://doi.org/10.1101/109785
Constraining CD45 exclusion at close-contacts provides a mechanism for discriminatory T-cell receptor signalling
Ricardo A Fernandes, Kristina A Ganzinger, Justin Tzou, Peter Jönsson, Steven F Lee, Matthieu Palayret, Ana Mafalda Santos, Veronica T Chang, Charlotte Macleod, B. Christoffer Lagerholm, Alan E. Lindsay, Omer Dushek, Andreas Tilevik, Simon J Davis, David Klenerman
bioRxiv 109785; doi: https://doi.org/10.1101/109785
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