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Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates

Steve O’Hagan, View ORCID ProfileDouglas B. Kell
doi: https://doi.org/10.1101/110437
Steve O’Hagan
1School of Chemistry, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
2Manchester Institute of Biotechnology, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
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Douglas B. Kell
1School of Chemistry, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
2Manchester Institute of Biotechnology, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
3Centre for the Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
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  • ORCID record for Douglas B. Kell
  • For correspondence: dbk@manchester.ac.uk
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Posted February 22, 2017.
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Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates
Steve O’Hagan, Douglas B. Kell
bioRxiv 110437; doi: https://doi.org/10.1101/110437
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Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates
Steve O’Hagan, Douglas B. Kell
bioRxiv 110437; doi: https://doi.org/10.1101/110437

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