Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Laminar organization of encoding and memory reactivation in the parietal cortex

Aaron A. Wilber, Ivan Skelin, Bruce L. McNaughton
doi: https://doi.org/10.1101/110684
Aaron A. Wilber
Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL, 32308 USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: iskelin@uci.edu awilber@fsu.edu
Ivan Skelin
Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, Lethbridge, AB, T1K 3M4 CanadaDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: iskelin@uci.edu awilber@fsu.edu
Bruce L. McNaughton
Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, Lethbridge, AB, T1K 3M4 CanadaDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Egocentric neural coding has been observed in parietal cortex (PC), but its topographical and laminar organization is not well characterized. We used multi-site recording to look for evidence of local clustering and laminar consistency of linear and angular velocity encoding in multi-neuronal spiking activity (MUA) and in the high-frequency (300-900 Hz) component of the local field potential (HF-LFP), believed to reflect local spiking activity. Rats were trained to run many trials on a large circular platform, either to LED-cued goal locations or as a spatial sequence from memory. Tuning to specific self-motion states was observed consistently, and exhibited distinct cortical depth-invariant coding properties. These patterns of collective local and laminar activation during behavior were reactivated in compressed form during post-experience sleep, and temporally coupled to hippocampal sharp wave ripples. Thus, PC neuron motion encoding is consistent across cortical laminae, and this consistency is maintained during memory reactivation.

Highlights

  • Parietal cortex MUA encodes specific movements coherently across laminae.

  • This organizational scheme is maintained during subsequent memory reactivation

  • MUA and HF-LFP showed similar self-motion tuning and memory reactivation dynamics

  • This establishes the utility of MUA and HF-LFP for human memory reactivation studies

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Back to top
PreviousNext
Posted June 16, 2017.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Laminar organization of encoding and memory reactivation in the parietal cortex
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
Share
Laminar organization of encoding and memory reactivation in the parietal cortex
Aaron A. Wilber, Ivan Skelin, Bruce L. McNaughton
bioRxiv 110684; doi: https://doi.org/10.1101/110684
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Laminar organization of encoding and memory reactivation in the parietal cortex
Aaron A. Wilber, Ivan Skelin, Bruce L. McNaughton
bioRxiv 110684; doi: https://doi.org/10.1101/110684

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (1533)
  • Biochemistry (2492)
  • Bioengineering (1747)
  • Bioinformatics (9700)
  • Biophysics (3915)
  • Cancer Biology (2979)
  • Cell Biology (4213)
  • Clinical Trials (135)
  • Developmental Biology (2639)
  • Ecology (4108)
  • Epidemiology (2033)
  • Evolutionary Biology (6911)
  • Genetics (5224)
  • Genomics (6519)
  • Immunology (2193)
  • Microbiology (6974)
  • Molecular Biology (2765)
  • Neuroscience (17348)
  • Paleontology (126)
  • Pathology (430)
  • Pharmacology and Toxicology (709)
  • Physiology (1062)
  • Plant Biology (2498)
  • Scientific Communication and Education (646)
  • Synthetic Biology (832)
  • Systems Biology (2691)
  • Zoology (433)