Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants

View ORCID ProfileWaring Trible, Ni-Chen Chang, View ORCID ProfileBenjamin J Matthews, Sean K McKenzie, Leonora Olivos-Cisneros, View ORCID ProfilePeter R Oxley, Jonathan Saragosti, Daniel JC Kronauer
doi: https://doi.org/10.1101/112532
Waring Trible
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Waring Trible
  • For correspondence: wtrible@rockefeller.edu
Ni-Chen Chang
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Benjamin J Matthews
2Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, NY 10065, USA
3Howard Hughes Medical Institute
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Benjamin J Matthews
Sean K McKenzie
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Leonora Olivos-Cisneros
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter R Oxley
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Peter R Oxley
Jonathan Saragosti
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel JC Kronauer
1Laboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY 10065, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Life inside ant colonies is orchestrated with a diverse set of pheromones, but it is not clear how ants perceive these social cues. It has been proposed that pheromone perception in ants evolved via expansions in the numbers of odorant receptors (ORs) and antennal lobe glomeruli. Here we generate the first mutant lines in ants by disrupting orco, a gene required for the function of all ORs. We find that orco mutants exhibit severe deficiencies in social behavior and fitness, suggesting that they are unable to perceive pheromones. Surprisingly, unlike in Drosophila melanogaster, orco mutant ants also lack most of the approximately 500 antennal lobe glomeruli found in wild-types. These results illustrate that ORs are essential for ant social organization, and raise the possibility that, similar to mammals, receptor function is required for the development and/or maintenance of the highly complex olfactory processing areas in the ant brain.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted February 28, 2017.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants
Waring Trible, Ni-Chen Chang, Benjamin J Matthews, Sean K McKenzie, Leonora Olivos-Cisneros, Peter R Oxley, Jonathan Saragosti, Daniel JC Kronauer
bioRxiv 112532; doi: https://doi.org/10.1101/112532
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants
Waring Trible, Ni-Chen Chang, Benjamin J Matthews, Sean K McKenzie, Leonora Olivos-Cisneros, Peter R Oxley, Jonathan Saragosti, Daniel JC Kronauer
bioRxiv 112532; doi: https://doi.org/10.1101/112532

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Evolutionary Biology
Subject Areas
All Articles
  • Animal Behavior and Cognition (2505)
  • Biochemistry (4951)
  • Bioengineering (3452)
  • Bioinformatics (15127)
  • Biophysics (6854)
  • Cancer Biology (5357)
  • Cell Biology (7681)
  • Clinical Trials (138)
  • Developmental Biology (4502)
  • Ecology (7110)
  • Epidemiology (2059)
  • Evolutionary Biology (10178)
  • Genetics (7491)
  • Genomics (9750)
  • Immunology (4801)
  • Microbiology (13131)
  • Molecular Biology (5109)
  • Neuroscience (29289)
  • Paleontology (203)
  • Pathology (832)
  • Pharmacology and Toxicology (1454)
  • Physiology (2116)
  • Plant Biology (4714)
  • Scientific Communication and Education (1002)
  • Synthetic Biology (1332)
  • Systems Biology (3993)
  • Zoology (766)