Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Differences in the spatial and temporal patterns of head motion during MRI of adults and infants

View ORCID ProfileRhodri Cusack, View ORCID ProfileAnnika C. Linke, View ORCID ProfileLeire Zubiaurre-Elorza, Hester Duffy, View ORCID ProfileCharlotte Herzmann, Bobby Stojanoski, View ORCID ProfileVictor K. Han, David S.C. Lee, View ORCID ProfileConor Wild
doi: https://doi.org/10.1101/114447
Rhodri Cusack
1Brain and Mind Institute, Western University, London, Canada
2Children’s Health Research Institute, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rhodri Cusack
Annika C. Linke
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Annika C. Linke
Leire Zubiaurre-Elorza
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Leire Zubiaurre-Elorza
Hester Duffy
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charlotte Herzmann
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Charlotte Herzmann
Bobby Stojanoski
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Victor K. Han
2Children’s Health Research Institute, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Victor K. Han
David S.C. Lee
2Children’s Health Research Institute, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Conor Wild
1Brain and Mind Institute, Western University, London, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Conor Wild
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Aim Head motion has a profound effect on MRI, and will contaminate comparisons of function or structure between groups that move differently. This work compares adults and infants. Infants might move differently for physical, physiological and cognitive reasons, but so far these differences have not been quantified.

Methods The spatial modes and total magnitude of motion in the MRI scanner were measured (N=211). The effects of group (infant vs. adult) and stimulation paradigm (auditory vs. visual) were evaluated.

Results Spatial modes of motion were found to be distinct between infant and adult groups. Infants had less anterior-posterior translational motion, but greater motion in other dimensions, often with complex multi-axis patterns. In magnitude distribution, sleeping infants often remained more still than adults, but when movement did occur it was more extreme and abrupt. Two groups of adults presented with different stimulation showed similar shapes of motion.

Conclusion The spatial modes and magnitude distribution of motion differed substantially between groups, and must be considered carefully as a confound in comparisons of structure or function. The abruptness and magnitude of movement suggests that for infants relative to adults post-processing strategies such as de-noising are likely to be more effective than prospective motion correction.

Key notes

  • Quantified the spatial and temporal distribution of motion during MRI in 211 adults and neonates

  • The different spatial modes in adults and infants were visualized and statistically contrasted

  • The magnitude of motion had “heavier tails” in infants, with more still periods, and more large movements, than adults.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted March 06, 2017.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Differences in the spatial and temporal patterns of head motion during MRI of adults and infants
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Differences in the spatial and temporal patterns of head motion during MRI of adults and infants
Rhodri Cusack, Annika C. Linke, Leire Zubiaurre-Elorza, Hester Duffy, Charlotte Herzmann, Bobby Stojanoski, Victor K. Han, David S.C. Lee, Conor Wild
bioRxiv 114447; doi: https://doi.org/10.1101/114447
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Differences in the spatial and temporal patterns of head motion during MRI of adults and infants
Rhodri Cusack, Annika C. Linke, Leire Zubiaurre-Elorza, Hester Duffy, Charlotte Herzmann, Bobby Stojanoski, Victor K. Han, David S.C. Lee, Conor Wild
bioRxiv 114447; doi: https://doi.org/10.1101/114447

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (4117)
  • Biochemistry (8820)
  • Bioengineering (6523)
  • Bioinformatics (23470)
  • Biophysics (11798)
  • Cancer Biology (9216)
  • Cell Biology (13327)
  • Clinical Trials (138)
  • Developmental Biology (7440)
  • Ecology (11417)
  • Epidemiology (2066)
  • Evolutionary Biology (15160)
  • Genetics (10442)
  • Genomics (14051)
  • Immunology (9176)
  • Microbiology (22170)
  • Molecular Biology (8817)
  • Neuroscience (47600)
  • Paleontology (350)
  • Pathology (1429)
  • Pharmacology and Toxicology (2492)
  • Physiology (3733)
  • Plant Biology (8084)
  • Scientific Communication and Education (1437)
  • Synthetic Biology (2221)
  • Systems Biology (6039)
  • Zoology (1254)