Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

A Transformation From Latency To Ensemble Coding In A Model Of Piriform Cortex

Merav Stern, Kevin Bolding, LF Abbott, Kevin Franks
doi: https://doi.org/10.1101/118364
Merav Stern
Hebrew University of Jerusalem;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kevin Bolding
Duke University;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
LF Abbott
Columbia University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kevin Franks
Duke University;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: franks@neuro.duke.edu
  • Abstract
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

We present a spiking network model that transforms odor-dependent variable-latency olfactory bulb responses into a cortical ensemble code. In the model, which captures basic circuit properties of piriform cortex, the impact of the earliest-activated bulb inputs on the cortical response is amplified by diffuse recurrent collateral excitation which then recruits strong feedback inhibition that stabilizes cortical activity and decreases the impact of later-responding glomeruli. Because the sequence of olfactory bulb activity for a particular odor is preserved across concentration, the ensemble of activated cortical neurons is robust to concentration changes. Nevertheless, odor concentration is represented by the latency and synchrony of the ensemble response. Using decoding techniques, we show that the ensemble-based coding scheme that arises in the cortical model supports concentration-invariant odor recognition.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted March 20, 2017.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
A Transformation From Latency To Ensemble Coding In A Model Of Piriform Cortex
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
Share
A Transformation From Latency To Ensemble Coding In A Model Of Piriform Cortex
Merav Stern, Kevin Bolding, LF Abbott, Kevin Franks
bioRxiv 118364; doi: https://doi.org/10.1101/118364
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
A Transformation From Latency To Ensemble Coding In A Model Of Piriform Cortex
Merav Stern, Kevin Bolding, LF Abbott, Kevin Franks
bioRxiv 118364; doi: https://doi.org/10.1101/118364

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (996)
  • Biochemistry (1485)
  • Bioengineering (938)
  • Bioinformatics (6803)
  • Biophysics (2414)
  • Cancer Biology (1782)
  • Cell Biology (2514)
  • Clinical Trials (106)
  • Developmental Biology (1683)
  • Ecology (2553)
  • Epidemiology (1488)
  • Evolutionary Biology (5003)
  • Genetics (3598)
  • Genomics (4614)
  • Immunology (1157)
  • Microbiology (4222)
  • Molecular Biology (1617)
  • Neuroscience (10744)
  • Paleontology (81)
  • Pathology (236)
  • Pharmacology and Toxicology (407)
  • Physiology (552)
  • Plant Biology (1445)
  • Scientific Communication and Education (410)
  • Synthetic Biology (542)
  • Systems Biology (1868)
  • Zoology (257)